American Airlines Flights from Detroit (DTW) to Key West (EYW)

ebookers are proud to offer some of the lowest fares on American Airlines flights from Detroit to Key West. With our low price guarantee you can book that flight to EYW with confidence today. Choose from some of the best days to fly with our flexible booking calendar and you’ll save even more money on your journey from DTW to EYW. Whether you’re on the way to a well-deserved vacation or just flying for business, take advantage of these airfare deals today and go and smell the roses!