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Hotel Santa Regina

3.0 star property
VIP Access

Choose dates to view prices

Photo gallery for Hotel Santa Regina

A hotel room with a bed, nightstands, a lamp, a red door, a bathroom, and a wooden spiral staircase.
A narrow street with parked cars and buildings on either side.
Interior
A room with a round table, two chairs, a vase with flowers, a wall-mounted light fixture, and a door with a window.
A hotel facade with large windows, a prominent entrance, and a sign indicating it is a hotel.

Reviews

8.8 out of 10
Excellent

Popular amenities

  • Free Wi-Fi
  • Laundry room
  • Housekeeping
  • 24/7 front desk

Explore the area

View in a map
Calle Alonso #26, Guanajuato, GTO, 36000
  • Place, University of Guanajuato
    ‪2 min walk‬
  • Place, Union Garden
    ‪2 min walk‬
  • Place, Alley of the Kiss
    ‪3 min walk‬
  • Airport, León, Guanajuato (BJX-Del Bajío)
    ‪38 min drive‬
VIP Access
Curated for quality and service, VIP Access stays consistently receive our highest guest ratings.
  • Expect exceptional service
  • Extra savings and perks for BONUS+ members
Learn more about VIP AccessOpens in a new window

Room options

View all photos for Double Room (1)

Two single beds with black frames and white bedding, a nightstand with a lamp, and a wooden door.

Double Room (1)

9.0 out of 10
Wonderful
(7 reviews)
  • 36 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free Wi-Fi

View all photos for Family Room (1)

A hotel room with a large bed, a television mounted on the wall, a staircase, and a window.

Family Room (1)

10.0 out of 10
Exceptional
(2 reviews)
  • 36 sq m
  • 1 bedroom
  • Sleeps 6
  • 2 Double Beds and 1 King Bed
  • Free Wi-Fi

View all photos for Standard Room, 1 King Bed (1)

A hotel room with a bed, nightstands, a lamp, a red door, a bathroom, and a wooden spiral staircase.

Standard Room, 1 King Bed (1)

10.0 out of 10
Exceptional
(7 reviews)
  • 36 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Family Room

A room with two beds, wooden beams on the ceiling, and a red chair.

Family Room

9.0 out of 10
Wonderful
(2 reviews)
  • 36 sq m
  • 1 bedroom
  • Sleeps 6
  • 2 Double Beds and 1 King Bed
  • Free Wi-Fi

View all photos for Standard Room, 1 King Bed (2)

A hotel room with a bed, a desk, a chair, and a TV mounted on the wall.

Standard Room, 1 King Bed (2)

8.0 out of 10
Very good
(1 review)
  • 36 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Standard Room, 1 King Bed (3)

A hotel room with a bed, a desk, a chair, and a TV mounted on the wall.

Standard Room, 1 King Bed (3)

  • 36 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Double Room (5)

A room with two beds, wooden beams on the ceiling, and a red chair.

Double Room (5)

9.0 out of 10
Wonderful
(2 reviews)
  • City view
  • 36 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free Wi-Fi

View all photos for Double Room (4)

A room with two beds, wooden beams on the ceiling, and a red chair.

Double Room (4)

10.0 out of 10
Exceptional
(1 review)
  • 36 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free Wi-Fi

View all photos for Double Room (3)

A room with two beds, wooden beams on the ceiling, and a red chair.

Double Room (3)

10.0 out of 10
Exceptional
(2 reviews)
  • City view
  • 36 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free Wi-Fi

View all photos for Double Room (2)

A room with two beds, wooden beams on the ceiling, and a red chair.

Double Room (2)

8.0 out of 10
Very good
(1 review)
  • 36 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds
  • Free Wi-Fi

Standard Room, 1 King Bed (4)

  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

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About this property

Hotel Santa Regina

A fridge in a common area, concierge services and laundry facilities are available at this smoke-free hotel. Free buffet breakfast and free WiFi in public areas are also provided. Additionally, a 24-hour front desk and tour/ticket assistance are on-site. Change of towels is available on request
Hotel Santa Regina offers 7 accommodations with a safe and a hairdryer. 32-inch flat-screen televisions come with cable channels.

Bathrooms include a shower and complimentary toiletries. Guests can surf the web using complimentary wireless Internet access. Additionally, rooms include a ceiling fan and blackout curtains. An iron/ironing board and change of towels can be requested. Housekeeping is provided on a daily basis.

Our customers tell us that they can't get enough of the helpful staff at Hotel Santa Regina. During your stay, you're just a quick walk from Alley of the Kiss. Features include free breakfast and free WiFi in public areas, plus concierge services.
  • Free buffet breakfast served daily
  • Free WiFi
  • Services include a concierge, tour or ticket assistance and luggage storage
  • Steps from La Paz Square and Basilica of Our Lady of Guanajuato
Free breakfast is served daily. WiFi is free in public spaces. Hotel Santa Regina also features tour/ticket assistance, concierge services, and laundry facilities.

This 3-star Guanajuato hotel is smoke free.

Guests are served a free buffet breakfast daily from 8:00 AM to 11:30 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • No on-site parking available

Food and drink

  • Free buffet breakfast available daily 8:00 AM to 11:30 AM

Family friendly

  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Luggage storage
  • Shared refrigerator
  • Water dispenser

Guest services

  • Change of towels on request
  • Concierge services
  • Housekeeping (daily)
  • Tour and ticket assistance

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Lift
  • Wheelchair accessibility

More

  • Mosquito nets
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower
  • Towels provided

Entertainment

  • 32-inch flat-screen TV with cable channels

More

  • Ceiling fan
  • Iron/ironing board on request
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; check-in end time: midnight
Contactless check-in and check-out are available
Late check-in subject to availability
Minimum check-in age - 18

Check-out

Check-out before noon
Contactless check-out

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets and service animals are not allowed at Hotel Santa Regina

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types at the property

Important information

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector
Front desk staff will greet guests on arrival at the property.
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.

We should mention

  • Pets and service animals are not allowed on site.

Property is also known as

Hotel Santa Regina
Hotel Santa Regina Guanajuato
Santa Regina Guanajuato
Santa Regina
Hotel Santa Regina Hotel
Hotel Santa Regina Guanajuato
Hotel Santa Regina Hotel Guanajuato

Hotel Santa Regina Reviews

Reviews

8.8

Excellent

Rating 10 - Excellent. 445 out of 782 reviews
Rating 8 - Good. 245 out of 782 reviews
Rating 6 - Okay. 57 out of 782 reviews
Rating 4 - Poor. 19 out of 782 reviews
Rating 2 - Terrible. 16 out of 782 reviews

9.4/10

Cleanliness

9.2/10

Staff & service

8.8/10

Amenities

8.8/10

Property conditions & facilities

Reviews

Verified

8/10 Good

MI

Liked: Cleanliness
Good location and great breakfast.
Stayed 3 nights in Dec 2025
Verified

10/10 Excellent

Jose A Diaz De

Liked: Cleanliness, amenities, property conditions & facilities
Hotel was very close to historic center and staff was very helpful
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Eric

Liked: Cleanliness, property conditions & facilities
Room was clean, staff was helpful, location is great.
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

Javier Gerardo

Liked: Cleanliness, staff & service, amenities
Todo excelente
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Carlos

Liked: Cleanliness, amenities, property conditions & facilities
I love it especially the front desk guy at night had the best service ever thank you will stay again
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Pankaj Kumar Omprakash

Liked: Property conditions & facilities
Nice hotel to stay
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Charles

Liked: Cleanliness, amenities, property conditions & facilities
Simple but clean with a complementary bottle of wine
Stayed 4 nights in Feb 2026
Verified

10/10 Excellent

Gamaliel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place
Stayed 1 night in Jul 2025
Verified

10/10 Excellent

miguel

Liked: Cleanliness, staff & service, property conditions & facilities
Great place to stay
Stayed 2 nights in Mar 2023
Verified

6/10 Okay

Kim Fah

Central location. Walk around at leisure in the zeno centro area. Many cafes/restaurants around. Breakfast is at another hotel within walking distance. Our room 27 has 1 double bed upstairs and 1 double bed downstairs. The one downstairs can close the bathroom door to outside traffic or noise from outside, but not the upstairs.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Julius

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I really enjoyed my stay at this hotel. Jesus, at the front desk was amazing. I loved the rooms and the proximity to everything. I have already booked this hotel again in May 2026. If i had one suggestion, it would be to have the breakfast vouchers valid at more than one place.
Stayed 4 nights in Dec 2025
Verified

8/10 Good

Thierno Sadou

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I will recommend it . At the heart of the downtown. Walking distance at all the mains attractions .Friendly staff
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

Sonia

Liked: Cleanliness, staff & service, amenities
Great service
Stayed 1 night in Dec 2025
Verified

8/10 Good

Sarna

Liked: Cleanliness, staff & service
Nice hotel, excellent staff, breakfast location was a short walk from the hotel, great area in the historic district. The mattresses could use replacing and if your bothered by late night noise, you’ll want to choose a different property.
Stayed 6 nights in Jan 2026
Verified

10/10 Excellent

Edward

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great hotel
Stayed 3 nights in Nov 2024
Verified

10/10 Excellent

Brian Alfonso

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excelente hotel
Stayed 1 night in Nov 2024
Verified

8/10 Good

Grace

Liked: Cleanliness, staff & service, amenities
Jesús and Rosie were wonderful and very knowledgeable. Clean room.
Stayed 7 nights in Jan 2026
Verified

10/10 Excellent

Martha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Todo excelente.
Stayed 3 nights in Oct 2025
Verified

10/10 Excellent

Mark

Liked: Cleanliness, staff & service, property conditions & facilities
Hotel Santa Regina is located close to many restaurants, bars, attraction, museums, and many places to shop.
Stayed 2 nights in Oct 2024
Verified

10/10 Excellent

Jose

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice place to stay and to walk around
Stayed 1 night in Dec 2022
Verified

10/10 Excellent

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Centró Guanajuato

Excellent centro location. Breakfast, other property, was great
Stayed 3 nights in Jul 2025
Verified

10/10 Excellent

Benito

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place to stay, very clean, very friendly staff, walking distance to good restaurants and main downtown places to see.
Stayed 2 nights in Jul 2022
Verified

10/10 Excellent

GERMAN

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excelente todo
Stayed 1 night in Jul 2025
Verified

6/10 Okay

Rosendo

Disliked: Property conditions & facilities
The location
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Humberto

Liked: Cleanliness, staff & service, property conditions & facilities
The hotel is located in the center of the the town and is very convenient to walk to the main attractions in downtown
Stayed 1 night in Sep 2023