See all properties

Hilton Jacksonville At Mayo Clinic

4.5 star property

Choose dates to view prices

Photo gallery for Hilton Jacksonville At Mayo Clinic

Breakfast, lunch, dinner served; American cuisine
Lobby
Lobby
Lake view
Terrace/patio

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Pool
  • Parking included
  • Free Wi-Fi
  • Restaurant
  • Air-conditioning
  • Gym

Explore the area

View in a map
4745 Transformation Way, Jacksonville, FL, 32224
  • Place, Mayo Clinic Florida
    ‪1 min walk‬
  • Place, St. Johns Town Center
    ‪7 min drive‬
  • Place, Mayport Naval Station
    ‪17 min drive‬
  • Airport, Jacksonville, FL (JAX-Jacksonville Intl.)
    ‪32 min drive‬

Room options

View all photos for Room, 1 King Bed

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed

8.0 out of 10
Very good
(3 reviews)
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed (Water View)

View from room

Deluxe Room, 1 King Bed (Water View)

  • Water view
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)

View from room

Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)

  • Sleeps 2
  • 1 King Bed

View all photos for Junior Suite, 1 King Bed

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Junior Suite, 1 King Bed

  • Sleeps 4
  • 1 King Bed

View all photos for Junior Suite, 1 King Bed, Corner

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Junior Suite, 1 King Bed, Corner

  • Sleeps 4
  • 1 King Bed

View all photos for Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

  • Sleeps 2
  • 1 King Bed

View all photos for Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)

  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed (Zero Count)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed (Zero Count)

  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed (Water View)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed (Water View)

9.0 out of 10
Wonderful
(2 reviews)
  • Water view
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed (Water View, Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed (Water View, Roll-In Shower)

  • Water view
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Accessible (Hearing)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed, Accessible (Hearing)

  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Accessible (Roll-In Shower)

Room, 1 King Bed, Accessible (Roll-In Shower) | Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed, Accessible (Roll-In Shower)

  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Accessible (Hearing)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed, Accessible (Hearing)

  • Sleeps 2
  • 1 King Bed

View all photos for Room, 2 Queen Beds

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds

9.6 out of 10
Exceptional
(21 reviews)
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible (Water View, Hearing)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds, Accessible (Water View, Hearing)

  • Water view
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible, Bathtub

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds, Accessible, Bathtub

10.0 out of 10
Exceptional
(1 review)
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible (Hearing)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds, Accessible (Hearing)

8.0 out of 10
Very good
(1 review)
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds (Water View)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds (Water View)

10.0 out of 10
Exceptional
(1 review)
  • Water view
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible, Bathtub (View)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds, Accessible, Bathtub (View)

  • Sleeps 4
  • 2 Queen Beds

Similar properties

Exterior
Hyatt Regency Jacksonville
  • Pool
  • Pet-friendly
  • Free Wi-Fi
  • Restaurant
4.5 out of 5, Wonderful, 1,522 reviews
The price is €209
includes taxes & fees
16 Mar - 17 Mar
Hyatt Regency Jacksonville

About this property

Hilton Jacksonville At Mayo Clinic

Along with an outdoor pool, this smoke-free hotel has a restaurant and a fitness centre. Free WiFi in public areas, free self parking and a free area shuttle are also provided. Other amenities include a bar/lounge, conference space and concierge services.
Hilton Jacksonville At Mayo Clinic offers 252 air-conditioned accommodations with laptop-compatible safes and complimentary bottles of water. Beds feature premium bedding. 55-inch Smart televisions come with premium cable channels and Netflix. Bathrooms include baths or showers and hairdryers.

Guests can surf the web using the complimentary wireless Internet access (speed: 25+ Mbps). Business-friendly amenities include telephones; local and long-distance calls are complimentary (restrictions may apply). Additionally, rooms include coffee/tea makers and an iron/ironing board. Housekeeping is provided on a daily basis.

Recreational amenities at the hotel include an outdoor pool and a fitness centre.

Children aged under 16 years old are not allowed in the swimming pool without adult supervision. Guests aged under 16 years old are not allowed in the fitness facility.

During your stay at Hilton Jacksonville At Mayo Clinic, you're just a quick walk from Mayo Clinic Florida. Free WiFi in public areas, free self-parking and a free area shuttle are available.
  • Free Wi-Fi (speed: 25+ Mbps)
  • Free self-parking
  • Enjoy American cuisine while dining at Coastal Kitchen
  • Buffet breakfast served daily for a fee
  • Take a swim in the outdoor pool
  • Services include dry cleaning/laundry, a concierge and a porter
  • On-site recreation includes a gym
  • Just a 2-minute drive from Mayo Clinic Florida and 8 minutes from St. Johns Town Center
  • Free local-area shuttle service
Hilton Jacksonville At Mayo Clinic offers its guests an outdoor pool and a fitness centre. There's a restaurant on site. You can enjoy a drink at the bar/lounge. Public spaces have free WiFi.

Business amenities include 12 meeting rooms and coworking spaces. Event space at this hotel measures 20000 square feet (1858 square metres) and includes conference space. The luxury Hilton Jacksonville At Mayo Clinic also features concierge services, laundry facilities, and dry cleaning/laundry services. A free area shuttle within 350 yards is available. Self parking is free.

This 4.5-star Jacksonville hotel is smoke free.

For a fee, guests can enjoy a buffet breakfast daily from 6:00 AM to 10:30 AM.
Coastal Kitchen – This restaurant specialises in American cuisine and serves breakfast, lunch and dinner. Guests can enjoy drinks at the bar. A children's menu is available.
Coastal Kitchen Bar – On-site cocktail bar. Open daily.
Late-night fare is available from room service (during limited hours).

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • In-room WiFi speed: 25+ Mbps
  • Available in some public areas: Free WiFi

Parking and transport

  • Electric car charging station on site
  • Free area shuttle up to 350 yards
  • Free uncovered self parking on site
  • Limited on-site self parking

Food and drink

  • Daily buffet breakfast available 6:00 AM to 10:30 AM for a fee: USD 26.99 to 26.99 for adults and USD 15 to 21 for children
  • A bar/lounge
  • A restaurant

Restaurants on site

  • Coastal Kitchen
  • Coastal Kitchen Bar

Things to do

  • Gym
  • Outdoor pool
  • TV in common areas

Family friendly

  • Free area shuttle
  • Grocery/convenience store
  • In-room cot
  • Laundry facilities
  • Mini-fridge
  • Outdoor pool
  • Rollaway/extra bed (surcharge)

Conveniences

  • 24-hour front desk
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage

Guest services

  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop
  • Proposal/romance packages
  • Wedding services

Business services

  • 12 meeting rooms
  • 20,000 square feet of conference space
  • Coworking space

Outdoors

  • Firepit
  • Outdoor furniture
  • Pool loungers
  • Pool umbrellas

Accessibility

  • Tile flooring in public areas

More

  • 1 building
  • 8 floors
  • At least 80% lighting from LEDs
  • At least 80% of food locally-sourced
  • Built in 2025
  • Comprehensive food waste policy
  • Smoke-free property
  • Traditional architecture
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Blackout drapes
  • Free cot
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Bathtub or shower
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 55-inch smart TV with premium cable channels
  • Netflix
  • Streaming services

Food and drink

  • Coffee/tea maker
  • Free bottled water
  • Late-night room service
  • Mini-fridge

More

  • Air conditioning
  • Free local calls
  • Free long-distance calls
  • Heating
  • Iron/ironing board
  • Laptop-compatible safe
  • LED lighting
  • Mobile key entry
  • Phone
  • Recycling
  • Water-efficient showers
  • Water-efficient toilets

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 5:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM
Contactless check-out
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation
The credit card used to book the reservation must be presented by the cardholder at check-in along with matching photo identification, and other arrangements must be coordinated with the property prior to arrival
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed

Children and extra beds

  • Children are welcome.
  • Kids stay free! Up to 2 children aged 18 years old and younger stay free per registered adult when using existing bedding.
  • Rollaway/extra beds are available for USD 50.00 per night.
  • Free cots (infant beds)!

Payment types at the property

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Breakage deposit: USD 100 per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for buffet breakfast: approximately USD 26.99 to 26.99 for adults and USD 15 to 21 for children
  • Rollaway bed fee: USD 50.00 per night

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorise the guest's credit card prior to arrival.
Cashless transactions are available
Safety features at this property include a carbon monoxide detector, a fire extinguisher and a smoke detector
Guests arriving after 11:00 PM must make advance arrangements by contacting the property using the information on the booking confirmation. Front desk staff will greet guests on arrival at the property. The credit card used when booking the reservation must be presented by the cardholder at check-in along with matching photo ID. Other arrangements must be coordinated with the property prior to arrival.
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.

We should mention

  • Pool access available from 8:00 AM to 10:00 PM
  • Up to 2 children aged 18 years old and younger stay free per registered adult in the same room as the parent or guardian when using existing bedding.
  • Registered guests are the only ones allowed to be in guestrooms.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Hilton Jacksonville At Mayo Clinic Hotel
Hilton Jacksonville At Mayo Clinic Jacksonville
Hilton Jacksonville At Mayo Clinic Hotel Jacksonville

Hilton Jacksonville At Mayo Clinic Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 134 out of 164 reviews
Rating 8 - Good. 13 out of 164 reviews
Rating 6 - Okay. 6 out of 164 reviews
Rating 4 - Poor. 6 out of 164 reviews
Rating 2 - Terrible. 5 out of 164 reviews

9.8/10

Cleanliness

9.8/10

Staff & service

9.4/10

Amenities

9.8/10

Property conditions & facilities

Reviews

2/10 Terrible

Marckendy

Travelled with partner
Liked: Cleanliness, property conditions & facilities
Disliked: Amenities
Yes the room feel neglected, i caught a cold for sleeping with no heat.i called for help and the staff said the heat will come up itself i spent two night sleeping in the cold i brought a small comforter from Walmart which i forget in the room .0 star
Stayed 2 nights in Dec 2025

10/10 Excellent

Lourdes

Stayed 1 night in Dec 2025

8/10 Good

Judith

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Hotel was lovely and new. Need to address a couple of things. Trash cans too small; no make up mirror in bathroom; no stool or chair in extremely large bath and no hooks for clothes in bathroom.
Stayed 2 nights in Dec 2025

10/10 Excellent

Josel

Stayed 1 night in Nov 2025

10/10 Excellent

Tonya, Bellevue

Stayed 1 night in Nov 2025

10/10 Excellent

Mark

Liked: Cleanliness, staff & service, property conditions & facilities
Clean. Very friendly staff.
Stayed 1 night in Nov 2025

10/10 Excellent

Leroy

Travelled with family, Business traveller
Liked: Cleanliness, amenities, property conditions & facilities
Everything was absolutely amazing. I definitely will be returning as soon as possible.
Stayed 1 night in Nov 2025

8/10 Good

Deborah

Travelled with family
Liked: Cleanliness, property conditions & facilities
Sound of air handler system was loud
Stayed 3 nights in Oct 2025

10/10 Excellent

Deborah

Stayed 2 nights in Nov 2025

10/10 Excellent

Jermaine, panama city

Travelled with partner, Travelled with group
Liked: Cleanliness, amenities, property conditions & facilities
Overall my stay was wonderful. Any concerns that I needed was addressed ASAP. Staff was friendly and helpful. I will stay here again.
Stayed 1 night in Nov 2025

10/10 Excellent

Ruben Dario

Stayed 1 night in Nov 2025

10/10 Excellent

Patty

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful hotel. Close to Mayo Clinic.
Stayed 2 nights in Nov 2025

10/10 Excellent

Kyle

Travelled with partner
Liked: Cleanliness, amenities
Everything in this brand new hotel is Beautifully designed. Elegant. Only complaint is doors slam to rooms!
Stayed 3 nights in Nov 2025

10/10 Excellent

Varun

Travelled with family
Liked: Cleanliness, amenities
Lot of efforts taken to make guests feel special and comfortable. Special thoughts were given to address many minor details. Breakfast had lot of variety and the pool was open till 10 PM. It was perfect for staying during family vacation.
Stayed 3 nights in Nov 2025

10/10 Excellent

Juan Carlos

Stayed 4 nights in Nov 2025

10/10 Excellent

Pratul

Liked: Cleanliness, amenities, property conditions & facilities
Room was spotless. Friendly staff
Stayed 2 nights in Nov 2025

10/10 Excellent

NaJai

Liked: Cleanliness, staff & service, amenities
Everything was so perfect ! The staff was amazing! Everything was spotless . 10/10 I recommend! I will definitely be back ! 😇
Stayed 2 nights in Nov 2025

10/10 Excellent

Aubrey Thomas

Liked: Cleanliness, property conditions & facilities
Great experience. Beautiful lobby
Stayed 1 night in Nov 2025

10/10 Excellent

Dwayne

Travelled with family, Business traveller
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful New Property!
Stayed 1 night in Nov 2025

10/10 Excellent

Josephine

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
It was quite, extremely clean.
Stayed 2 nights in Nov 2025

10/10 Excellent

Joseph

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Beautiful, comfortable, clean. Restfully furnished. Great service to the Mayo Clinic.
Stayed 3 nights in Nov 2025

10/10 Excellent

milan

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Nov 2025

10/10 Excellent

Aaron

Liked: Cleanliness, amenities, property conditions & facilities
Room was spotless and staff was extremely professional
Stayed 1 night in Nov 2025

10/10 Excellent

Leslie

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Want to thank the wait staff at bar. They were very helpful and friendly. They made our stressful day much better.
Stayed 1 night in Nov 2025

10/10 Excellent

Jo, Brunswick

Business traveller, Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Everything was absolutely fantastic!!! Room, staff, decor, restaurant. Stayed here for an early procedure at Mayo Clinic, Jacksonville, FL.
Stayed 1 night in Nov 2025