See all properties

Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property

Choose dates to view prices

Photo gallery for Residence Inn Durham McPherson/Duke University Medical Cntr

An outdoor patio with wicker furniture, a stone fire pit, and a brick building in the background.
A multi-story brick building with a modern entrance and a parking lot.
A hotel room with two beds, a desk, a TV, and a sofa.
Fitness facility
Lobby lounge

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Pet-friendly
  • Free Wi-Fi
  • Air-conditioning
  • Parking available

Explore the area

View in a map
1108 West Main Street, Durham, NC, 27701
  • Place, Brightleaf Square
    ‪3 min walk‬
  • Place, Duke University
    ‪3 min walk‬
  • Place, Durham Performing Arts Center
    ‪16 min walk‬
  • Airport, Raleigh, NC (RDU-Raleigh - Durham Intl.)
    ‪19 min drive‬

Room options

View all photos for Suite, 1 Bedroom

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

8.8 out of 10
Excellent
(6 reviews)
  • 44 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free Wi-Fi

View all photos for Studio, 1 King Bed with Sofa bed

A modern hotel room with a bed, a desk, a chair, a television, and a small table.

Studio, 1 King Bed with Sofa bed

9.0 out of 10
Wonderful
(37 reviews)
  • 45 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio, 1 Queen Bed with Sofa bed

A modern hotel room with a bed, a TV, a kitchenette, and a dining area.

Studio, 1 Queen Bed with Sofa bed

9.8 out of 10
Exceptional
(16 reviews)
  • 39 sq m
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Suite, 1 Bedroom (Hearing Accessible)

A hotel room with a bed, a desk, a chair, and a TV.

Suite, 1 Bedroom (Hearing Accessible)

8.8 out of 10
Excellent
(3 reviews)
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free Wi-Fi

View all photos for Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

A modern hotel room with a bed, a desk, a chair, a television, and a small table.

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

10.0 out of 10
Exceptional
(1 review)
  • 44 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

A modern hotel room with a bed, a desk, a chair, a television, and a small table.

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

  • 45 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio, 1 King Bed with Sofa bed (Hearing Accessible)

A modern hotel room with a bed, a desk, a chair, a television, and a small table.

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

  • 45 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

A hotel room with a bed, a desk, a chair, and a TV.

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

  • 40 sq m
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Suite, Multiple Beds (Mobility Accessible, Tub)

A hotel room with two beds, a flat-screen TV mounted on the wall, a wooden headboard, and a window with sheer curtains.

Suite, Multiple Beds (Mobility Accessible, Tub)

8.0 out of 10
Very good
(2 reviews)
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Suite, 1 Bedroom (Mobility Accessible, Roll-in Shower)

A hotel room with a bed, a desk, a chair, and a TV.

Suite, 1 Bedroom (Mobility Accessible, Roll-in Shower)

10.0 out of 10
Exceptional
(1 review)
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed
  • Free Wi-Fi

Similar properties

Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, desk, blackout curtains, iron/ironing board
Comfort Inn & Suites Durham near Duke University
Croasdaile Farm Master
  • Pool
  • Breakfast included
  • Parking included
  • Free Wi-Fi
4.3 out of 5, Excellent, 1,081 reviews
The price is €92
includes taxes & fees
2 Aug - 3 Aug
Comfort Inn & Suites Durham near Duke University

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

Along with a 24-hour fitness centre, this smoke-free hotel has coffee/tea in a common area and a business centre. Free on-the-go breakfast, free WiFi in public areas and a free area shuttle are also provided. Other amenities include self parking, conference space and concierge services. Housekeeping is available on request.
Residence Inn Durham McPherson/Duke University Medical Cntr offers 147 accommodations with a safe and coffee/tea makers. This accommodation offers separate sitting areas and includes dining tables. 32-inch Smart televisions come with premium cable channels, pay-per-view films and Netflix. Accommodation at this 3-star hotel has kitchens with full-sized fridge/freezers, stovetops, microwaves and kitchenware and utensils. Bathrooms include a combined bath/shower unit, complimentary toiletries and hairdryers.

This Durham hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and desk chairs, as well as telephones; free local calls are provided (restrictions may apply). Additionally, rooms include an iron/ironing board and blackout curtains. Change of towels and change of bedsheets can be requested. Housekeeping is provided on a daily basis.

Recreational amenities at the hotel include a 24-hour fitness centre.

Children aged under 18 years old are not allowed in the swimming pool or fitness facility without adult supervision. Guests aged under 18 years old are not allowed in the fitness facility.

Our customers tell us that they can't get enough of the helpful staff at Residence Inn Durham McPherson/Duke University Medical Cntr. During your stay, you're just a quick walk from Duke University. Enjoy features like free breakfast, free WiFi in public areas and a free area shuttle.
  • Free on-the-go breakfast served daily
  • Free WiFi
  • Self-parking available for a fee
  • Services include free food shopping service, dry cleaning/laundry and a concierge
  • On-site recreation includes a 24-hour gym
  • Steps from Duke University and a 3-minute drive from Durham Performing Arts Center
  • Free local-area shuttle service
  • Pets welcome for a fee (restrictions apply)
A computer station is on site and WiFi is free in public spaces. You'll find a business centre on site. Free breakfast is available daily. Event space at this hotel measures 2530 square feet (235 square metres) and includes conference space. A 24-hour fitness centre, a terrace, and coffee/tea in common area are also featured at the business-friendly Residence Inn Durham McPherson/Duke University Medical Cntr. The hotel can provide concierge services, a complimentary food/drink shopping service, and wedding services. Parking is available for a fee. A complete renovation of Residence Inn Durham McPherson/Duke University Medical Cntr was completed in April 2024.

This 3-star Durham hotel is smoke free.

Guests are served a free on-the-go breakfast daily from 7:00 AM to 9:00 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Free area shuttle
  • Parking on site (USD 15 per day)
  • Limited on-site self parking
  • Wheelchair-accessible parking available

Food and drink

  • Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
  • Coffee and tea in common areas

Things to do

  • 24-hour gym

Family friendly

  • Dining table
  • Free area shuttle
  • Grocery/convenience store
  • In-room full-sized refrigerator/freezer
  • In-room kitchen
  • In-room microwave
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Wedding services

Business services

  • 2,530 square feet of conference space
  • Business centre
  • Computer station

Outdoors

  • Terrace

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 7 accessible parking spaces
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Hardwood flooring in room
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Thin carpet in room
  • Visual alarms in hallways
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business centre
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible registration desk (86 centimetre high)
  • Wheelchair-accessible restaurant

More

  • 5 floors
  • Banquet hall
  • Built in 2015
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • No plastic drinking straws
  • Non-plastic coffee stirrers available
  • Renovated entire property - April 2024
  • Smoking not allowed
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 32-inch smart TV with premium cable channels
  • Netflix
  • Pay films

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dining table
  • Dishwasher
  • Full-sized refrigerator/freezer
  • Hob
  • Kitchen
  • Microwave

More

  • Air conditioning (climate-controlled)
  • Desk
  • Desk chair
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Phone
  • Recycling
  • Safe
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; check-in end time: midnight
Express check-in available
Minimum check-in age - 21

Check-out

Check-out before noon
Contactless check-out
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 100.00 per pet (varies based on length of stay)
  • Maximum 2 (weight limit: 100 lb per pet)
  • Restrictions apply
  • For more information, you can reach out to the property at the number on the booking confirmation
    • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types at the property

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Self-parking fee: USD 15 per day
  • Pet fee: USD 100.00 per pet (varies based on length of stay)
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)
Front desk staff will greet guests on arrival at the property.
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.

We should mention

  • To make arrangements to bring your pet, contact the property directly at the number on your booking confirmation (please see the Fees section for related charges).
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn Durham McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 328 out of 484 reviews
Rating 8 - Good. 109 out of 484 reviews
Rating 6 - Okay. 29 out of 484 reviews
Rating 4 - Poor. 7 out of 484 reviews
Rating 2 - Terrible. 11 out of 484 reviews

9.4/10

Cleanliness

9.2/10

Staff & service

8.8/10

Amenities

9.4/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

RICHARD

Liked: Cleanliness, staff & service, property conditions & facilities
Great downtown location
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Anna F

Liked: Cleanliness, amenities, property conditions & facilities
Courteous staff, spotless rooms, comfortable bed and pillows.
Stayed 4 nights in Dec 2025
Verified

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was great - very friendly staff.
Stayed 2 nights in Sep 2025
Verified

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities
We love this hotel. The staff is excellent and the rooms are well designed and comfortable. The breakfast is delicious.
Stayed 10 nights in Dec 2025
Verified

10/10 Excellent

Syreeta

Liked: Cleanliness, staff & service, amenities
Rooms were spacious and spotless. Customer Service was phenomenal! Housekeeping were friendly and had no problems giving the extra items needed, including extra pillows.
Stayed 2 nights in Feb 2026
Verified

8/10 Good

Minor

Liked: Cleanliness, staff & service
An excellent place to stay!
Stayed 1 night in Feb 2025
Verified

10/10 Excellent

Tim

Liked: Cleanliness, staff & service, amenities
Great stay. The hotel breakfast left a little something to be desired but the room was clean, the staff was helpful. This was everything I expected.
Stayed 2 nights in Nov 2025
Verified

6/10 Okay

Susan

Liked: Cleanliness, amenities, property conditions & facilities
Wi-Fi did not work and we were not told the procedure for paying for parking. Received a $20 ticket.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Judy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location with some incredible Restaurants nearby
Stayed 3 nights in Oct 2024
Verified

10/10 Excellent

Derek

Liked: Cleanliness, staff & service, property conditions & facilities
Was very nice. The staff was very polite when we arrived.
Stayed 1 night in Aug 2025
Verified

10/10 Excellent

Margaret

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great and reasonably priced place to stay as a family in the center of Durham.
Stayed 1 night in Sep 2024
Verified

10/10 Excellent

Jackson

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice clean room,good breakfast and great staff.
Stayed 4 nights in Nov 2022
Verified

8/10 Good

James

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice hotel for the price. Good location. Big rooms. Quiet. Easy parking. Could be a little cleaner.
Stayed 2 nights in Oct 2025
Verified

10/10 Excellent

Wendy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, friendly, great location.
Stayed 1 night in Sep 2024
Verified

10/10 Excellent

Christopher

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place!
Stayed 3 nights in Dec 2023
Verified

10/10 Excellent

Jo Anne

Liked: Cleanliness, staff & service, property conditions & facilities
Great place
Stayed 2 nights in May 2024
Verified

10/10 Excellent

Hong

Liked: Cleanliness, staff & service, property conditions & facilities
Nice staff, very helpful. Close to Duke University, great place to stay.
Stayed 6 nights in Jan 2025
Verified

10/10 Excellent

LaMeesha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.
Stayed 8 nights in Jun 2025
Verified

8/10 Good

Heman

Liked: Cleanliness, amenities, property conditions & facilities
Laura and Tiffany were extremely helpful and accommodating. The whole staff was very friendly and welcoming!
Stayed 9 nights in Jul 2025
Verified

10/10 Excellent

Timmy

Liked: Cleanliness, amenities, property conditions & facilities
It was very clean and the staff was excellent. The stay was really good. The attendant was great at checking.
Stayed 1 night in Jun 2025
Verified

10/10 Excellent

Mustafa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
comfortable stay
Stayed 3 nights in Nov 2023
Verified

10/10 Excellent

Barbara

Liked: Cleanliness, staff & service, property conditions & facilities
Breakfast was great.
Stayed 3 nights in Jan 2024
Verified

10/10 Excellent

Timothy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great location in Durham!
Stayed 1 night in Apr 2024
Verified

10/10 Excellent

Kelly

Liked: Property conditions & facilities
Very nice staff and very clean!
Stayed 1 night in Feb 2024
Verified

10/10 Excellent

Gonzalo

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice hotel convenient for visiting Duke
Stayed 1 night in Apr 2023

Hotels

Flights

Packages