21C Museum Hotel St Louis

4.5 star property

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Room options

View all photos for Deluxe Room, 1 King Bed

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(82 reviews)
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

Luxury Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, blackout curtains

Luxury Double Room, 2 Queen Beds

9.2 out of 10
Wonderful
(24 reviews)
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room (Bunk Bed)

In-room safe, desk, laptop workspace, blackout curtains

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Single Bunk Bed

View all photos for Loft, 2 Queen Beds

In-room safe, desk, laptop workspace, blackout curtains

Loft, 2 Queen Beds

8.0 out of 10
Very good
(1 review)
  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds

View all photos for Deluxe Room, Accessible (Accessible)

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Room, Accessible (Accessible)

  • 25 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (21C)

Suite, 1 King Bed (21C) | In-room safe, desk, laptop workspace, blackout curtains

Suite, 1 King Bed (21C)

  • 104 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library) | In-room safe, desk, laptop workspace, blackout curtains

Suite, 1 King Bed (Library)

  • 68 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed | In-room safe, desk, laptop workspace, blackout curtains

Luxury Suite, 1 King Bed

10.0 out of 10
Exceptional
(1 review)
  • 51 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 Double Bed, Accessible

Deluxe Room, 1 Double Bed, Accessible | In-room safe, desk, laptop workspace, blackout curtains

Deluxe Room, 1 Double Bed, Accessible

  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Suite, 1 Double Bed, Accessible

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Suite, 1 Double Bed, Accessible

  • 48 sq m
  • Sleeps 2
  • 1 Double Bed

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About this property

21C Museum Hotel St Louis

Luxury hotel with fitness centre and steam room
This smoke-free hotel features an indoor pool, a restaurant and a fitness centre. WiFi in public areas is free. Additionally, a bar/lounge, a steam room and a coffee shop/cafe are on-site. Change of towels is available on request
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and a safe. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries and hairdryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs and telephones. Additionally, rooms include complimentary bottles of water and an iron/ironing board. Change of towels and change of bedsheets can be requested. Housekeeping is provided on a daily basis.

Recreational amenities at the hotel include an indoor pool, a steam room and a fitness centre.
Guests can pamper themselves by indulging in the on-site spa services. Services include massages.
Our customers tell us they can't get enough of 21C Museum Hotel St Louis 's great location. During your stay, you're just a quick walk from St. Louis Union Station. Enjoy features like free WiFi in public areas, plus an indoor pool and a restaurant.
  • Free WiFi
  • Drinking and dining options include a coffee shop, a restaurant and a bar/lounge
  • Cooked-to-order breakfast served daily for a fee
  • Valet parking available for a fee
  • Take a swim in the indoor pool
  • Services include dry cleaning/laundry, a concierge and luggage storage
  • On-site recreation includes a gym and a steam room
  • Guests have great things to say about the helpful staff and the location
  • Within a 10-minute walk of St. Louis Union Station and City Museum
  • Dogs welcome for a fee
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness centre. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business centre and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

For a fee, guests can enjoy a cooked-to-order breakfast daily from 6:30 AM to 1:00 PM.
21C Museum Hotel St Louis has a restaurant on site.
Room service (during limited hours) is available.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)
  • Limited on-site valet parking

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
    • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types at the property

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Front desk staff will greet guests on arrival at the property.
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 1111 out of 1554 reviews
Rating 8 - Good. 236 out of 1554 reviews
Rating 6 - Okay. 106 out of 1554 reviews
Rating 4 - Poor. 47 out of 1554 reviews
Rating 2 - Terrible. 54 out of 1554 reviews

9.2/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

Reviews

10/10 Excellent

KEVIN

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Oct 2025

10/10 Excellent

Lora

Stayed 1 night in Oct 2025

10/10 Excellent

Lyndsey

Stayed 1 night in Oct 2025

8/10 Good

Melissa

Travelled with family
Liked: Cleanliness
Some things missing from room and we called the front desk but they never showed up. The air conditioner was very loud and kept us up. The pool area was great but out of towels.
Stayed 1 night in Oct 2025

10/10 Excellent

Tiffany

Liked: Cleanliness, staff & service, property conditions & facilities
Beautiful space, unique atmosphere and very clean.
Stayed 1 night in Oct 2025

6/10 Okay

Royal

Travelled with partner
Liked: Staff & service, amenities, property conditions & facilities
Disliked: Cleanliness
We had doubts our room had been cleaned. The shower had large globs of hair on the walls. The rest of the bathroom also left question marks, I flushed toilet, hair on counter and in sink. We were in a rush and didn’t have time to address concerns with staff before our event. We just avoided the bathroom when we returned.
Stayed 1 night in Oct 2025

10/10 Excellent

Sonali

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Lovely place
Stayed 2 nights in Oct 2025

10/10 Excellent

Timothy

Stayed 1 night in Oct 2025

10/10 Excellent

Michelle

Stayed 1 night in Oct 2025

10/10 Excellent

Kevin

Stayed 1 night in Oct 2025

4/10 Poor

Hillary

Liked: Cleanliness
Disliked: Staff & service, property conditions & facilities, room comfort
A/C was disabled in our room. Staff didn’t seem to care after asking twice. We forgot items in our room and no one will assist to get them back to us. Beautiful hotel should have amazing hospitality. Hospitality was not present at all within the hotel.
Stayed 2 nights in Oct 2025

6/10 Okay

Hillary

Disliked: Staff & service
IdolWolf bar & restaurant is perfect. Beautiful menus for dinner, brunch & cocktails. Upon arrival at the hotel, knew it wasn’t realistic for early check in. We were told $65 for early check in, we were fine with that. Checked our luggage with their 3rd party valet service, we had an appointment scheduled that we needed to leave for. When we came back later that evening, we were able to get checked in and move our luggage to the room. The next day we were unpacking and came to find that we were missing almost $500 in cash. This beautiful hotel that we had a wonderful stay in back in June, we were beyond disappointed. We raised the issue with the staff. They rerouted us to the 3rd party valet. They did take care of a the valet charges, but nothing else came to fruition to make us whole on what was stolen from us. We followed up at checkout and they upgraded us to a suite for when we check back in the next day. We did need to book a different room due to no availability for one night. We checked back in, and when we arrived to our room, the a/c was completely disabled, it was broken. We called the front desk twice that day asking for it to be fixed. We were told that they were full and couldn’t move us. We checked out, followed up on the stolen cash. Reminded them to fix the a/c. We forgot some items in a drawer. We called and was told they’ll check with housekeeping. I called the manager. No return call. We just want our items returned to us. We are happy to pay shipping.
Stayed 5 nights in Oct 2025

10/10 Excellent

Joel

Stayed 1 night in Oct 2025

10/10 Excellent

Vicki

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Oct 2025

10/10 Excellent

Jemma

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
My stay there was great. The staff were so friendly and accommodating.
Stayed 1 night in Oct 2025

10/10 Excellent

anthony

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Love the 21C. I try staying here every time I’m in St. Louis. There’s a great restaurant, a full art gallery and a steam room / gym as well. The staff is always super accommodating.
Stayed 1 night in Oct 2025

8/10 Good

Alex

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The room was clean and spacious. However, the information is not accurate—you need to pay additional $50 for parking.
Stayed 1 night in Sep 2025

10/10 Excellent

Rachel

Stayed 1 night in Sep 2025

10/10 Excellent

Rhonda

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great location downtown and the best valet service.
Stayed 1 night in Oct 2025

2/10 Terrible

William

Disliked: Staff & service, room comfort

Unethical Hotel - avoid

We booked and paid for a suite through Hotels.com, but when we arrived, the air conditioning wasn’t working. It was a warm day, and after three separate requests for help, nothing was done. Hours later, just before we left for the concert we came to see, I went to the front desk when they finally admitted they couldn’t fix it. Their “solution” was to move us — not to another suite(one wasn’t available), but to the a small basic room. We didn’t have time to switch before the concert, so after a long night out we came back tired, only to have to pack up all our things and move rooms ourselves. The room we were moved to was dramatically smaller, and their idea of compensation was offering us free breakfast. The difference in cost between the suite we paid for and the basic room we were given was significant — not to mention the complete disruption to our stay. When I went to the desk to discuss a refund, the employee couldn’t have been less interested in helping. Hotels.com tried to assist but explained that the hotel refused to authorize a refund, so their hands were tied. At the end of the day, this hotel charged us for a suite they couldn’t provide, wasted our time, and made no real effort to make things right. The lack of accountability and basic customer service was astonishing. There are plenty of places to stay that actually value their guests — this isn’t one of them. Avoid it.
Stayed 1 night in Oct 2025

10/10 Excellent

Rodney

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Museum and a hotel, very clean, incredible pool and amenities area.
Stayed 1 night in Oct 2025

10/10 Excellent

april

Liked: Cleanliness, staff & service, property conditions & facilities
Beautiful Hotel.
Stayed 3 nights in Sep 2025

6/10 Okay

alphonzia

Liked: Cleanliness, property conditions & facilities, room comfort
No hot tub
Stayed 2 nights in Oct 2025

10/10 Excellent

Scott

Stayed 2 nights in Sep 2025

10/10 Excellent

Keri

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Sep 2025