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Holiday Inn Express & Suites St. Louis South - I-55 by IHG

2.5 star property

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Photo gallery for Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Property amenity
Exterior
Fitness facility
Free daily buffet breakfast
Property amenity

Reviews

9.6 out of 10
Exceptional

Popular amenities

  • Free Wi-Fi
  • Air-conditioning

Explore the area

View in a map
4250 Midamerica Lane, St. Louis, MO, 63129
  • Place, Busch Stadium
    ‪16 min drive‬
  • Place, Gateway Arch
    ‪17 min drive‬
  • Place, St. Louis Union Station
    ‪18 min drive‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪29 min drive‬

Room options

View all photos for Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

Room amenity

Standard Room, 2 Queen Beds, Accessible (Comm, Bath Shwr Combo)

9.4 out of 10
Exceptional
(13 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

Standard Room, 2 Queen Beds, Accessible (Mobil Tub) | In-room safe, desk, laptop workspace, blackout curtains

Standard Room, 2 Queen Beds, Accessible (Mobil Tub)

9.6 out of 10
Exceptional
(4 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for Suite, 1 Bedroom (2 Queen, Extra Living Area)

Room amenity

Suite, 1 Bedroom (2 Queen, Extra Living Area)

9.6 out of 10
Exceptional
(32 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 6
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

Room amenity

Standard Room, 1 King Bed, Accessible (Comm, Bath Shower Combo)

9.0 out of 10
Wonderful
(7 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free Wi-Fi

View all photos for Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

Free toiletries, hair dryer, towels, soap

Standard Room, 1 King Bed, Accessible (Mobil Roll In Shwr)

10.0 out of 10
Exceptional
(2 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Suite, 1 King Bed (Extra Living, Walk in Shwr)

Suite, 1 King Bed (Extra Living, Walk in Shwr) | In-room safe, desk, laptop workspace, blackout curtains

Suite, 1 King Bed (Extra Living, Walk in Shwr)

9.2 out of 10
Wonderful
(5 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free Wi-Fi

View all photos for Standard Room, 1 King Bed (Bath Shwr Combo)

Room amenity

Standard Room, 1 King Bed (Bath Shwr Combo)

9.6 out of 10
Exceptional
(17 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free Wi-Fi

View all photos for Standard Room

Standard Room | In-room safe, desk, laptop workspace, blackout curtains

Standard Room

  • 28 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Single Bed
  • Free Wi-Fi

View all photos for Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living) | In-room safe, desk, laptop workspace, blackout curtains

Suite, 1 King Bed, Accessible (Mobil Tub, Extra Living)

  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free Wi-Fi

View all photos for Standard Room, 2 Queen Beds

Room amenity

Standard Room, 2 Queen Beds

9.6 out of 10
Exceptional
(78 reviews)
  • 28 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

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About this property

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Along with an indoor pool, this smoke-free hotel has a 24-hour fitness centre and a business centre. Free buffet breakfast, free WiFi in public areas and free self parking are also provided. Additionally, a 24-hour front desk, a front desk safe and a banquet hall are on-site. Housekeeping is available on request.
Holiday Inn Express & Suites St. Louis South - I-55 by IHG offers 99 accommodations with a safe and coffee/tea makers. 49-inch flat-screen televisions come with cable channels. Guests can make use of the in-room fridges and microwaves. Bathrooms include complimentary toiletries and hairdryers.

Guests can surf the web using complimentary wired and wireless Internet access. Business-friendly amenities include desks and telephones; free local calls are provided (restrictions may apply). Additionally, rooms include an iron/ironing board and blackout curtains. Change of towels and change of bedsheets can be requested. Housekeeping is provided on a daily basis.

Recreational amenities at the hotel include an indoor pool and a 24-hour fitness centre.
The free breakfast at Holiday Inn Express & Suites St. Louis South - I-55 by IHG gets high marks from our customers. During your stay, you're just a quick walk from Barnes Jewish South Campus. You'll find features such as free WiFi in public areas and free self-parking, plus an indoor pool.
  • Free buffet breakfast served daily
  • Free WiFi
  • Free self-parking
  • Take a swim in the indoor pool
  • Amenities include a front desk safe, a business centre and meeting rooms
  • On-site recreation includes a 24-hour gym
  • Guests have great things to say about the clean guestrooms and the breakfast
  • Just a 1-minute drive from Barnes Jewish South Campus and 6 minutes from St Anthony's
Holiday Inn Express & Suites St. Louis South - I-55 by IHG offers its guests an indoor pool and a 24-hour fitness centre. Public spaces have free WiFi. A business centre and meeting rooms are available. Free breakfast is served daily. The business-friendly Holiday Inn Express & Suites St. Louis South - I-55 by IHG also features a vending machine, a front desk safe, and a lift. Self parking is free.

This St. Louis hotel is smoke free.

Guests are served a free buffet breakfast daily from 6:00 AM to 9:30 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi

Parking and transport

  • Free self parking on site
  • Limited on-site self parking
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 9:30 AM

Things to do

  • 24-hour gym
  • Indoor pool

Family friendly

  • In-room cot
  • In-room microwave
  • In-room refrigerator
  • Indoor pool

Conveniences

  • 24-hour front desk
  • Safe at front desk
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Lift
  • Stair-free path to entrance
  • Visual alarms in hallways
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible van parking

More

  • 4 floors
  • At least 10% of profits reinvested in community and sustainability
  • Banquet hall
  • No plastic drinking straws
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Free cot

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 49-inch flat-screen TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe

Policies

Check-in

Check-in start time: 3:00 PM; check-in end time: 2:30 AM
Minimum check-in age - 21

Check-out

Check-out before 11 AM
Contactless check-out

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed, but service animals are welcome

Children and extra beds

  • Children are welcome.
  • Free cots (infant beds)!

Payment types at the property

Important information

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Front desk staff will greet guests on arrival at the property.
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.

We should mention

  • Pool access available from 8 AM to 10 PM
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express St. Louis South I-55 Hotel
Holiday Inn Express St. Louis South I-55
Inn Express St Louis I55
Holiday Inn Express Suites St. Louis South I 55
Holiday Inn Express Suites St. Louis South I 55 by IHG
Holiday Inn Express Suites St. Louis South I 55 an IHG Hotel
Holiday Inn Express & Suites St. Louis South - I-55 by IHG Hotel

Holiday Inn Express & Suites St. Louis South - I-55 by IHG Reviews

Reviews

9.6

Exceptional

Rating 10 - Excellent. 805 out of 1004 reviews
Rating 8 - Good. 141 out of 1004 reviews
Rating 6 - Okay. 36 out of 1004 reviews
Rating 4 - Poor. 15 out of 1004 reviews
Rating 2 - Terrible. 7 out of 1004 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.6/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Adam

Liked: Cleanliness, amenities, property conditions & facilities
Great stay
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Kelsey

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Desk staff was very friendly, room was nice and clean, kids loved the pool, breakfast was great!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

George

Liked: Cleanliness, staff & service, amenities
Clean rooms, great friendly staff, very good breakfast with lots to choose from
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

HEATHER

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The place was clean, the pool was functional, the food was decent, and my kids favorite part was the cookie hour! Will definitely pick this hotel when we come back to the St Louis area!
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Mary

Liked: Cleanliness, staff & service, amenities
The room is clean, the bed and pillows are super comfy and the breakfast is great! I travel to the area a few times a year for work and this is my new favorite place to stay.
Stayed 4 nights in Feb 2026
Verified

10/10 Excellent

Mitch

Liked: Cleanliness, staff & service, property conditions & facilities
It was great!
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Janice

Liked: Cleanliness, staff & service, amenities
Enjoyed the cleanliness and comfort of the bed and room and the friendly staffand the freshly roasted coffeecofrrroascoffee
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

James

Clean room, location, excellent staff
Stayed 4 nights in Dec 2025
Verified

10/10 Excellent

Anita

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was clean and staff was friendly.
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

Terri

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely clean comfortable hotel. The only improvement would if streaming on TV was possible. But overall an excellent hotel
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

James

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and nice.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Shelby

Liked: Cleanliness, staff & service, property conditions & facilities
Great
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Pamela

Liked: Cleanliness, amenities, property conditions & facilities
Staff is very nice! The rooms are clean and comfortable.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Brandy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Friendly staff clean rooms
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Walt

Liked: Cleanliness, staff & service, property conditions & facilities
Easy to get there from the highway exit.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Ashley

Liked: Cleanliness, staff & service, amenities
Room was clean. Area was quiet. Cookie hour was nice and the breakfast had lots of options.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Roderick

Liked: Cleanliness, amenities, property conditions & facilities
A clean room and a nice room, with a nice bathroom, comfortable bed, tv with a good selection of channels free, the warm chocolate chip cookies with milk at 8 pm was very nice complimentary, and complimentary breakfast was very good! Staff was very friendly and helpful! Nice swimming pool
Stayed 1 night in Jan 2026
Verified

8/10 Good

Eleanor

Liked: Cleanliness, staff & service, amenities
Everything was clean. Coffee was great. Breakfast was better than expected. We will be staying at this hotel our next trip to St. Louis.
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

Arielle

Liked: Cleanliness, amenities, property conditions & facilities
Room was absolutely perfect…. Great space and very clean
Stayed 1 night in Dec 2025
Verified

8/10 Good

Therese

Liked: Cleanliness, staff & service, amenities
Clean rooms. Easy check-in. Great breakfast.
Stayed 4 nights in Dec 2025
Verified

10/10 Excellent

Jessica

Great breakfast, great rooms and comfy beds.
Stayed 1 night in May 2025
Verified

10/10 Excellent

Ray

Liked: Cleanliness, staff & service, property conditions & facilities
Great hotel
Stayed 6 nights in Jul 2025
Verified

10/10 Excellent

tiffany

Liked: Cleanliness, amenities, property conditions & facilities
Room was very clean! enjoyed the amenities!
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Jennifer

Liked: Cleanliness, amenities, property conditions & facilities
Everything was very clean. Breakfast was good. And coffee in the lobby was really appreciated. It has been a long time since I have stayed at a Holiday Inn Express but I'd definitely stay here again.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Kevin

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Had to make a 2 day trip to Wisconsin from Texas. As always we stayed at Holiday inn because we know we will get a nice clean place to stay with a good breakfast. Also we feel safe staying at your Hotels. Thanks to your staff, we had a worry free trip.
Stayed 2 nights in Jan 2026