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Featured Hotels near O Brien

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!

obrien FL
During your stay at this holiday home, you're just a quick walk from Suwannee River. You'll find features such as a gym, laundry facilities and an arcade/games room. The holiday home offers free WiFi and a kitchen.
10/10 Exceptional! (35 reviews)
We really enjoyed our stay. The host ( Christine) greeted us upon arrival and was eager to share recommendations for things to do in the area. The house was clean, comfortable, and well maintained. The whole family had a blast!

Reviewed on 23 Mar 2026

Opens in a new windowRoyal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

2 out of 5
1699 NE Co Rd 337 High Springs FL
The price is €198 per night from 31 Mar to 1 Apr
€198
31 Mar - 1 Apr
includes taxes & fees
During your stay at Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy, you'll be close to Ruth B. Kirby Gilchrist Blue Springs State Park. Features include free self-parking. This budget cabin has 45 cabins. This property offers pet-friendly amenities, such as food and water bowls. Each cabin includes amenities such as a kitchenette and a patio.
10/10 Exceptional! (190 reviews)
Perfect getaway for us with our dogs. It was peaceful and relaxing.

Reviewed on 24 Mar 2026

Opens in a new windowPostcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 out of 5
16367 NW 167TH BLVD Alachua FL
The price is €111 per night from 20 Apr to 21 Apr
€111
20 Apr - 21 Apr
includes taxes & fees
The free breakfast at Holiday Inn Express & Suites Alachua - Gainesville Area by IHG gets high marks from our customers. During your stay, you'll be close to Alachua Sports Complex. You'll find features such as free WiFi in public areas and free self-parking, plus an outdoor pool.
9.4/10 Exceptional! (1,001 reviews)
Heated pool and hot tub! Major plus and the breakfast was also awesome! Staff was very helpful and took great care of my family.

Reviewed on 25 Mar 2026

Opens in a new windowHoliday Inn Express & Suites Alachua - Gainesville Area by IHG
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Best Western Plus Lake City

Best Western Plus Lake City

2.5 out of 5
350 SW Florida Gateway Dr Lake City FL
The price is €92 per night from 29 Mar to 30 Mar
€92
29 Mar - 30 Mar
includes taxes & fees
The free breakfast at Best Western Plus Lake City gets good marks from our customers. During your stay, you'll be within walking distance of Lake City Mall. You'll find features such as free WiFi in public areas and free self-parking, plus an indoor pool.
9/10 Wonderful! (1,031 reviews)
Room was clean and well kept. The bed was very comfortable

Reviewed on 23 Mar 2026

Opens in a new windowBest Western Plus Lake City
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 out of 5
165NW CALI DRIVE Lake City FL
The price is €97 per night from 29 Mar to 30 Mar
€97
29 Mar - 30 Mar
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at La Quinta Inn & Suite by Wyndham Lake City. During your stay, you're just a quick walk from Fresenius Medical Care at Lake City Medical Center. You'll find features such as free WiFi in public areas and free self-parking, plus an indoor pool.
8.8/10 Excellent! (1,087 reviews)
We really hate the fan noice in the bathroom. It never stops!! Toilet seat was falling off. You would think the maids would notice. No hand soap left just an empty wrapper. We probably wouldn’t stay there again.

Reviewed on 21 Mar 2026

Opens in a new windowLa Quinta Inn & Suite by Wyndham Lake City
Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

2 out of 5
3835 West US Highway 90 Lake City FL
The price is €65 per night from 26 Mar to 27 Mar
€65
26 Mar - 27 Mar
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Americas Best Value Inn Lake City. During your stay, you'll be within walking distance of Lake Shore Primary Care West. You'll find features such as free breakfast, free WiFi in public areas and free self-parking.
8.6/10 Excellent! (1,003 reviews)
Clean Room

Reviewed on 24 Mar 2026

Opens in a new windowAmericas Best Value Inn Lake City
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.