Find Cheap Flights from Brussels (BRU) to Panama City (PTY) from €686

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Selected flight deals from Brussels to Panama City

The lowest prices found within the past 7 days from Brussels to Panama City were €538 for one-way flights and €686 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, 21 Jan - Sun, 25 Jan
BRU
Brussels - National
PTY
Tocumen Intl.
€686 Return, found 5 days ago
€686
Return
found 5 days ago
Select Air Europa flight, departing Wed, 21 Jan from Brussels - National to Tocumen Intl., returning Sun, 25 Jan, priced at €686 found 5 days ago
Mon, 23 Feb - Mon, 23 Feb
BRU
Brussels - National
PTY
Tocumen Intl.
€776 Return, found 4 days ago
€776
Return
found 4 days ago
Select Air Europa flight, departing Mon, 23 Feb from Brussels - National to Tocumen Intl., returning Mon, 23 Feb, priced at €776 found 4 days ago
Wed, 21 Jan - Sat, 24 Jan
BRU
Brussels - National
PTY
Tocumen Intl.
€780 Return, found 5 days ago
€780
Return
found 5 days ago
Select Lufthansa flight, departing Wed, 21 Jan from Brussels - National to Tocumen Intl., returning Sat, 24 Jan, priced at €780 found 5 days ago
Wed, 21 Jan - Sat, 24 Jan
BRU
Brussels - National
PTY
Tocumen Intl.
€785 Return, found 5 days ago
€785
Return
found 5 days ago
Select Lufthansa flight, departing Wed, 21 Jan from Brussels - National to Tocumen Intl., returning Sat, 24 Jan, priced at €785 found 5 days ago
Wed, 21 Jan - Sat, 24 Jan
BRU
Brussels - National
PTY
Tocumen Intl.
€788 Return, found 5 days ago
€788
Return
found 5 days ago
Select Swiss International Air Lines flight, departing Wed, 21 Jan from Brussels - National to Tocumen Intl., returning Sat, 24 Jan, priced at €788 found 5 days ago
Cheap Flights from Brussels to Panama City & Flight Information
Origin airport IATA code
BRU
Destination airport IATA code
PTY
Return price
€686

Best Day to Book Flight from Brussels to Panama City

Panama City Flight Information

Traveling From
Brussels
Origin Airport IATA Code
BRU
Traveling To
Panama City
Destination Airport IATA Code
PTY
Number of Airlines Serving
Available Airlines
Air Europa, Iberia, Lufthansa, Swiss International Air Lines, Delta, Air France
Distance
Direct Flight Time
Flight Price
€686

Need a car after flight from Brussels to Panama City

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

Place to stay after flight from Brussels to Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Yövy tässä ylellisessä hotellissa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja 3 ravintolasta. Asiakkaamme kehuvat majoituspaikan ...
9/10 Wonderful! (4,835 reviews)
Convenient hotel with a big pool

Reviewed on 14 Jan 2026

Opens in a new windowHotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Yövy tässä ylellisessä hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, täyden palvelun kylpylästä ja 2 ravintolasta. Asiakkaamme kehuvat majoituspaikan ...
8.8/10 Excellent! (1,004 reviews)
awesome location, great staff

Reviewed on 12 Jan 2026

Opens in a new windowWaldorf Astoria Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Yövy tässä kylpylälomalle soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta pysäköinnistä ja täyden palvelun kylpylästä. Asiakkaamme ...
7.6/10 Good! (998 reviews)
All very good and great value! Great location too.

Reviewed on 12 Jan 2026

Opens in a new windowHotel El Panama by Faranda Grand, a member of Radisson Individuals
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The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
Yövy tässä liikematkustukseen soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja ilmaisesta pysäköinnistä. ...
9.2/10 Wonderful! (1,005 reviews)
As always a wonderful stay . This is our go too hotel when in Panamá City . Just a great centrally located place with fantastic friendly staff.

Reviewed on 17 Jan 2026

Opens in a new windowThe Executive Hotel
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
Yövy tässä ylellisessä hotellissa kohteessa Panamá. Nauti 2 ravintolasta, 3 porealtaasta ja 2 baarista/loungesta. Asiakkaamme kehuvat majoituspaikan huomaavaista ...
8.8/10 Excellent! (1,004 reviews)
Suite was spacious, clean, and the staff was exceptional.

Reviewed on 16 Jan 2026

Opens in a new windowW Panama
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Av. Balboa con Calle 53 Panama City Panama
Yövy tässä kylpylälomalle soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, täyden palvelun kylpylästä ja aamiaisesta (lisämaksusta). ...
8.8/10 Excellent! (1,002 reviews)
Great staff, great room, great time in Panama

Reviewed on 17 Jan 2026

Opens in a new windowLas Americas Golden Tower Panama
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Terms & Conditions

Flight prices above are per person all prepaid taxes and online service fees included and subject to availability