Best 4 Star Hotels in Otay Mesa
Check availability on Otay Mesa 4 Star Hotels
Featured Otay Mesa 4 Stars Hotels

Hard Rock Hotel San Diego
207 5th Ave San Diego CA
The price is €272 per night
€272
11 Mar - 12 Mar
includes taxes & fees
Our customers tell us they can't get enough of Hard Rock Hotel San Diego's great location. During your stay, you're just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus 2 restaurants and 2 coffee shops/cafes.

Paradise Point Resort & Spa
1404 Vacation Rd San Diego CA
The price is €246 per night
€246
25 Mar - 26 Mar
includes taxes & fees
Our customers tell us they can't get enough of Paradise Point Resort & Spa's great beach location. During your stay, you'll be close to Mission Bay. Features include free WiFi in public areas, plus 5 outdoor pools and 2 restaurants.

Embassy Suites by Hilton San Diego Bay Downtown
601 Pacific Hwy San Diego CA
The price is €233 per night
€233
3 Apr - 4 Apr
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at Embassy Suites by Hilton San Diego Bay Downtown. During your stay, you're just a quick walk from Seaport Village. Features include a free manager's reception, plus an indoor pool and a restaurant.

San Diego Mission Bay Resort
1775 E Mission Bay Dr San Diego CA
The price is €282 per night
€282
8 Mar - 9 Mar
includes taxes & fees
San Diego Mission Bay Resort's great location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Bay. Features include free WiFi in public areas, plus 2 restaurants and a full-service spa. This property offers pet-friendly amenities, such as food and water bowls.

Hyatt Regency Mission Bay Spa and Marina
1441 Quivira Rd San Diego CA
The price is €211 per night
€211
11 Mar - 12 Mar
includes taxes & fees
Hyatt Regency Mission Bay Spa and Marina's great location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Bay. Enjoy features like free WiFi in public areas, plus 3 outdoor pools and 2 restaurants. This property offers pet-friendly amenities, such as food and water bowls.

Wyndham San Diego Bayside
1355 N Harbor Drive San Diego CA
The price is €181 per night
€181
19 Mar - 20 Mar
includes taxes & fees
The sightseeing around Wyndham San Diego Bayside gets high marks from our customers. During your stay, you're just a quick walk from Port of San Diego. You'll find features such as free WiFi in public areas and a free round-trip airport shuttle, plus 3 restaurants.

San Diego Marriott Gaslamp Quarter
660 K St San Diego CA
The price is €160 per night
€160
2 Apr - 3 Apr
includes taxes & fees
San Diego Marriott Gaslamp Quarter's great location gets high marks from our customers. During your stay, you're just a quick walk from Petco Park. You'll find features such as 2 bars, a restaurant and a 24-hour gym.

Lafayette Hotel & Club
2223 El Cajon Blvd San Diego CA
The price is €225 per night
€225
10 Mar - 11 Mar
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Lafayette Hotel & Club. During your stay, you'll be close to San Diego Zoo. Enjoy features like free WiFi in public areas, plus 2 restaurants and 3 bars.

Hotel Indigo San Diego-Gaslamp Quarter by IHG
509 9th Ave San Diego CA
The price is €195 per night
€195
3 Apr - 4 Apr
includes taxes & fees
Hotel Indigo San Diego-Gaslamp Quarter by IHG's great location gets high marks from our customers. During your stay, you're just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus 2 restaurants and 2 bars. This property offers pet-friendly amenities, such as food and water bowls.

Omni San Diego Hotel at the Ballpark
675 L St San Diego CA
The price is €232 per night
€232
8 Mar - 9 Mar
includes taxes & fees
Our customers tell us they can't get enough of Omni San Diego Hotel at the Ballpark's great location. During your stay, you'll be connected to the convention centre and just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus an outdoor pool and a restaurant.

Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
The price is €160 per night
€160
4 Apr - 5 Apr
includes taxes & fees
Our customers tell us they can't get enough of Sheraton San Diego Resort's great location. During your stay, you're just a quick walk from Naval Base Coronado. Free WiFi in public areas, a free round-trip airport shuttle and 3 outdoor pools are available. This property offers pet-friendly amenities, such as food and water bowls.

Marriott Marquis San Diego Marina
333 W Harbor Dr San Diego CA
The price is €244 per night
€244
2 Apr - 3 Apr
includes taxes & fees
Our customers tell us that they can't get enough of the pool at Marriott Marquis San Diego Marina. During your stay, you'll be connected to the convention centre and just a quick walk from Seaport Village. 2 outdoor pools, 5 restaurants and 2 bars are available.

Manchester Grand Hyatt San Diego
1 Market Pl San Diego CA
The price is €264 per night
€264
13 Mar - 14 Mar
includes taxes & fees
Manchester Grand Hyatt San Diego's great location gets high marks from our customers. During your stay, you're just a quick walk from Seaport Village. Enjoy features like free WiFi in public areas, plus 6 restaurants and 3 bars.

The Westin San Diego Bayview
1051 Columbia street San Diego CA
The price is €184 per night
€184
4 Apr - 5 Apr
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at The Westin San Diego Bayview. During your stay, you're just a quick walk from Port of San Diego. You'll find features such as free WiFi in public areas and a free round-trip airport shuttle, plus an outdoor pool. This property offers pet-friendly amenities, such as food and water bowls.

Margaritaville Hotel San Diego Gaslamp Quarter
435 6th Ave San Diego CA
The price is €226 per night
€226
8 Mar - 9 Mar
includes taxes & fees
Our customers tell us they can't get enough of Margaritaville Hotel San Diego Gaslamp Quarter's great location. During your stay, you're just a quick walk from Petco Park. Enjoy features like an outdoor pool, a restaurant and a 24-hour gym. This property offers pet-friendly amenities, such as food and water bowls.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Otay Mesa hotels essential information
Accommodation | 4,869 hotels |
|---|---|
Lowest Price | €160 |
Highest Price | €282 |
Popular hotels | Hard Rock Hotel San Diego, Paradise Point Resort & Spa, Embassy Suites by Hilton San Diego Bay Downtown, San Diego Mission Bay Resort, Hyatt Regency Mission Bay Spa and Marina, Wyndham San Diego Bayside, San Diego Marriott Gaslamp Quarter, Lafayette Hotel & Club, Hotel Indigo San Diego-Gaslamp Quarter by IHG, Omni San Diego Hotel at the Ballpark, Sheraton San Diego Resort, Marriott Marquis San Diego Marina, Manchester Grand Hyatt San Diego, The Westin San Diego Bayview, Margaritaville Hotel San Diego Gaslamp Quarter |
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