Find 3,716 hotels in San Diego Santa Fe Depot

The sightseeing around Wyndham San Diego Bayside gets high marks from our customers. During your stay, you're just a quick walk from Port of San Diego. Enjoy features like a free round-trip airport shuttle, plus 3 restaurants and an outdoor pool.

The Dana on Mission Bay's great beach location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Bay. You'll find features such as free WiFi in public areas, plus 2 outdoor pools and 2 poolside bars. This property offers pet-friendly amenities, such as food and water bowls.

Manchester Grand Hyatt San Diego's great location gets high marks from our customers. During your stay, you're just a quick walk from Seaport Village. Enjoy features like free WiFi in public areas, plus 6 restaurants and 3 bars.

Hyatt Regency Mission Bay Spa and Marina's great location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Bay. Enjoy features like free WiFi in public areas, plus 3 outdoor pools and 2 restaurants. This property offers pet-friendly amenities, such as food and water bowls.

Our customers tell us that they can't get enough of the helpful staff at Dextro, Little Italy, BW Premier Collection. During your stay, you're just a quick walk from San Diego Civic Theatre. Features include free WiFi in public areas, plus an outdoor pool and a restaurant.

Our customers tell us that they can't get enough of the free breakfast at Embassy Suites by Hilton San Diego Bay Downtown. During your stay, you're just a quick walk from USS Midway Museum. Features include a free manager's reception, plus an indoor pool and a restaurant.

Our customers tell us they can't get enough of Handlery Hotel's great location. During your stay, you'll be within walking distance of Fashion Valley Mall. Features include free WiFi in public areas, plus 2 restaurants and 2 bars.

Our customers tell us that they can't get enough of the pool at Hilton San Diego Bayfront. During your stay, you're just a quick walk from Petco Park. Free WiFi in public areas, 2 bars and a full-service spa are available.

Our customers tell us that they can't get enough of the pool at Marriott Marquis San Diego Marina. During your stay, you'll be connected to the convention centre and just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus 2 outdoor pools and 5 restaurants.

Our customers tell us that they can't get enough of the free breakfast at Hampton Inn San Diego/Mission Valley. During your stay, you'll be within walking distance of Hotel Circle. Free WiFi in public areas, an outdoor pool and a 24-hour gym are available.

Our customers tell us they can't get enough of Sheraton San Diego Resort's great location. During your stay, you're just a quick walk from San Diego Bay. Free WiFi in public areas, a free round-trip airport shuttle and 3 outdoor pools are available. This property offers pet-friendly amenities, such as food and water bowls.

Our customers tell us they can't get enough of Bay Club Hotel & Marina's great location. During your stay, you're just a quick walk from Shelter Island. You'll find features such as free WiFi in public areas, plus an outdoor pool and a restaurant.

Best Western Plus Marina Gateway Hotel's great location gets high marks from our customers. During your stay, you'll be within walking distance of San Diego Bay. You'll find features such as free WiFi in public areas and free self-parking, plus an outdoor pool.

Our customers tell us that they can't get enough of the helpful staff at The Little Italy Hotel Downtown San Diego. During your stay, you're just a quick walk from Waterfront Park. You'll find features such as free WiFi in public areas, plus a restaurant and a bar. This property offers pet-friendly amenities, such as an off-lead area.

Our customers tell us that they can't get enough of the helpful staff at Hotel del Coronado, Curio Collection by Hilton. During your stay, you're just a quick walk from Hotel del Coronado. Features include free WiFi in public areas, plus 6 restaurants and 3 bars. This property offers pet-friendly amenities, such as food and water bowls.