Find Cheap Flights from Madrid (MAD) to Panama City (PTY) from €705
Many airlines offer flexible change policies
Earn BONUS+ rewards on top of your airline points
Enjoy exclusive promotions on the ebookers app!
Selected flight deals from Madrid to Panama City
The lowest prices found within the past 7 days from Madrid to Panama City were €348 for one-way flights and €705 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.
MAD
Adolfo Suárez Madrid-Barajas
PTY
Tocumen Intl.
€705 Return, found 13 hours ago
€705
Return
found 13 hours ago
MAD
Adolfo Suárez Madrid-Barajas
PTY
Tocumen Intl.
€776 Return, found 13 hours ago
€776
Return
found 13 hours ago
MAD
Adolfo Suárez Madrid-Barajas
PTY
Tocumen Intl.
€783 Return, found 13 hours ago
€783
Return
found 13 hours ago
MAD
Adolfo Suárez Madrid-Barajas
PTY
Tocumen Intl.
€819 Return, found 13 hours ago
€819
Return
found 13 hours ago
MAD
Adolfo Suárez Madrid-Barajas
PTY
Tocumen Intl.
€830 Return, found 13 hours ago
€830
Return
found 13 hours ago
Origin airport IATA code | MAD |
|---|---|
Destination airport IATA code | PTY |
Number of flight options | 1 |
Return price | €704 |
Average flight time | 3 hours 50 mins |
Panama City Flight Information
Traveling From | Madrid |
|---|---|
Origin Airport IATA Code | MAD |
Traveling To | Panama City |
Destination Airport IATA Code | PTY |
Number of Airlines Serving | |
Available Airlines | avianca, Aeromexico, Iberia, Air Europa, KLM, American Airlines |
Distance | |
Direct Flight Time | |
Flight Price | €705 |
Need a car after flight from Madrid to Panama City
Economy
Chevrolet Spark
Compact
Ford Focus
Midsize
Toyota Corolla
SUV
Jeep Compass
Place to stay after flight from Madrid to Panama City
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
Yövy tässä ylellisessä hotellissa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja 3 ravintolasta. Asiakkaamme kehuvat majoituspaikan ...
9/10 Wonderful! (5,435 reviews)
Staff wasn’t. Etsy accommodating at check in but all others accommodations were great
Reviewed on 16 May 2026
The Executive Hotel
Calle 52 Panama City Panama
Yövy tässä liikematkustukseen soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja ilmaisesta pysäköinnistä. ...
9.2/10 Wonderful! (1,109 reviews)
The room was rather small and Hotel is centrally located. I will say that the highlight was the friendly staff. Just so you know come out of the rooms and bathrooms are pretty tiny, the balconies are pretty small as well so it’s a good spot if you’re looking to not stay super long or you are traveling ...
Reviewed on 16 May 2026
Principe Hotel and Suites
Via Argentina Panama City Panama
Yövy tässä liikematkustukseen soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja huonepalvelusta. Asiakkaamme ...
9/10 Wonderful! (1,857 reviews)
I couldn't get a response regarding an airport shuttle so contacted hotels.com who also failed. It was going to cost $30. My Uber cost less than $20. Clean room, but very uninviting and worn. AC was not on when I entered. It finally got too cold, but there was no way to adjust it. No coffee or water. ...
Reviewed on 16 May 2026
Save an average of 15% on thousands of hotels when you're signed in
Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Yövy tässä kylpylälomalle soveltuvassa aamiaismajoituksessa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja ilmaisesta pysäköinnistä. ...
8.8/10 Excellent! (918 reviews)
I stayed in one of the refurbished rooms. It was nice and clean for the most part. The staff replenished toiletries on a daily basis.
Reviewed on 16 May 2026
Hotel Ojos del Rio
calle 41 este Panama City Panama
Yövy tässä hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, aamiaisesta (lisämaksusta) ja huonepalvelusta. Asiakkaamme kehuvat majoituspaikan ...
8/10 Very Good! (1,007 reviews)
Stayed only one night. Overall hotel is good. It was clean. Location is great. Very good breakfast.
Reviewed on 15 May 2026
Courtyard by Marriott Panama Multiplaza Mall
Via Israel Multiplaza Pacific Mall Panama City Panama
Yövy tässä liikematkustukseen soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja aamiaisesta (lisämaksusta). ...
9/10 Wonderful! (1,006 reviews)
Todo
Reviewed on 15 May 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
- Madrid Airports
- Panama City Airports
- Other Flights to Panama City
- Other Flights from Madrid
- Top Trending
Top Trending
Flights
- Flights from Vienna to Marbella
- Flights from Helsinki to Burgos
- Flights from Helsinki to Girona
- Flights from Helsinki to Mallorca Island
- Flights from Vaasa to Gran Canaria
- Flights from Helsinki to Málaga
- Flights from Helsinki to Alicante
- Flights from Helsinki to Gran Canaria
- Flights from Helsinki to Las Palmas de Gran Canaria
- Flights from Helsinki to Fuengirola
- Flights from Tallinn to Tenerife
- Flights from Helsinki to La Palma
- Flights from Barcelona to Banjul
- Flights from Budapest to Marbella
- Flights from Tampere to Málaga
- Flights from Helsinki to Marbella
- Flights from Helsinki to Benidorm
- Flights from Tallinn to Las Palmas de Gran Canaria
- Flights from Helsinki to Jerez de la Frontera
- Flights from Tenerife to Helsinki
- Flights from Málaga to Helsinki
- Flights from Helsinki to Barcelona
- Flights from Helsinki to Tenerife
- Flights from Helsinki to Fuerteventura
- Flights from Helsinki to Lanzarote
- Flights from Helsinki to Sitges
- Flights from Málaga to Tenerife
- Flights from Helsinki to Seville
- Flights from Helsinki to La Gomera
- Flights from Stockholm to Málaga
Need more than a Flight from Madrid to Panama City?
Terms & Conditions
Flight prices above are per person all prepaid taxes and online service fees included and subject to availability