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Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

2.5 star property

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Photo gallery for Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

1 bedroom, in-room safe, desk, laptop workspace
Free daily buffet breakfast
Exterior
Free daily buffet breakfast
Check-in/check-out kiosk

Reviews

8.6 out of 10
Excellent

Popular amenities

  • Free Wi-Fi
  • Air-conditioning
  • Gym
  • Business services
  • Laundry room

Explore the area

View in a map
601 Main St, Buffalo, NY, 14203
  • Place, Chippewa District
    ‪1 min walk‬
  • Place, Shea's Performing Arts Center
    ‪2 min walk‬
  • Place, Buffalo Niagara Convention Center
    ‪6 min walk‬
  • Airport, Buffalo, NY (BUF-Buffalo Niagara Intl.)
    ‪22 min drive‬

Room options

View all photos for Standard Room

Standard Room | 1 bedroom, in-room safe, desk, laptop workspace

Standard Room

9.0 out of 10
Wonderful
(28 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Suite, 1 Bedroom

Suite, 1 Bedroom | 1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 Bedroom

8.8 out of 10
Excellent
(52 reviews)
  • City view
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed
  • Free Wi-Fi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

Combined shower/bathtub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Bathtub)

9.6 out of 10
Exceptional
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free Wi-Fi

View all photos for Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

Combined shower/bathtub, eco-friendly toiletries, hair dryer, towels

Suite, 1 Bedroom, Accessible (Mobility Accessible, Roll-in Shower)

9.0 out of 10
Wonderful
(4 reviews)
  • 46 sq m
  • 1 bedroom
  • Sleeps 4
  • 1 Queen Bed
  • Free Wi-Fi

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About this property

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

This smoke-free hotel features a fitness centre, a business centre and dry cleaning. Free buffet breakfast and free WiFi in public areas are also provided. Additionally, laundry facilities, a 24-hour front desk and express check-out are on-site.
Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG offers 146 accommodations with a safe and coffee/tea makers. This accommodation has separate sitting areas and is furnished with double sofa beds. Cable televisions are provided. Guests can make use of the in-room fridges and microwaves. Bathrooms include a combined bath/shower unit, complimentary toiletries and hairdryers.

This Buffalo hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and telephones; free local calls are provided (restrictions may apply). Additionally, rooms include an iron/ironing board and blackout curtains. Housekeeping is provided on a daily basis.

Recreational amenities at the hotel include a fitness centre.
Our customers tell us that they can't get enough of the helpful staff at Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG. During your stay, you're just a quick walk from Niagara Square. Features include free breakfast and free WiFi in public areas, plus a gym.
  • Free buffet breakfast served daily
  • Free WiFi
  • Amenities include a front desk safe, a business centre and laundry facilities
  • On-site recreation includes a gym
  • Guests have great things to say about the helpful staff and the clean guestrooms
  • Steps from Market Arcade Building and Buffalo Music Hall of Fame
Public spaces have free WiFi. You'll find a business centre on site. Free breakfast is available daily. A fitness centre, a vending machine, and laundry facilities are also featured at the business-friendly Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG.

This Buffalo hotel is smoke free.

Guests are served a free buffet breakfast daily from 6:00 AM to 10:00 AM.

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Offsite parking available (USD 16 per day)
  • Wheelchair-accessible parking and van parking available
  • Onsite parking options include a garage

Food and drink

  • Free buffet breakfast available daily 6:00 AM to 10:00 AM

Things to do

  • Gym

Family friendly

  • In-room cot
  • In-room microwave
  • In-room refrigerator
  • In-room sofa bed
  • Laundry facilities
  • Living room
  • Separate bedroom

Conveniences

  • 24-hour front desk
  • Guidebooks
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Grab bar in shower
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • In-room roll-in shower
  • Lever door handles
  • Lift
  • Low-height electrical sockets in bathroom
  • Portable shower seat
  • Raised toilet seat
  • Visual fire alarm
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible bathroom vanity
  • Wheelchair-accessible business centre
  • Wheelchair-accessible gym
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking

More

  • 7 floors
  • At least 80% lighting from LEDs
  • Comprehensive food waste policy
  • Eco-friendly cleaning products used
  • Smoke-free property
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes
  • Double sofa bed
  • Free cot

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 49-inch TV with cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Refrigerator
  • Restaurant dining guides

More

  • Air conditioning (climate-controlled)
  • Bulk dispensers for toiletries
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Living room
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; check-in end time: anytime
Contactless check-in and check-out are available
Minimum check-in age - 21

Check-out

Check-out before 11 AM
Contactless check-out
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • No pets allowed, but service animals are welcome

Children and extra beds

  • Children are welcome.
  • Kids stay free! Children 18 years old and younger stay free when using existing bedding.
  • Rollaway/extra beds are not available.
  • Free cots (infant beds)!

Payment types at the property

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Nearby parking fee: USD 16.00 per day (500 ft away)

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher, a smoke detector and window guards
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Please note that cultural norms and guest policies may differ by country and by property; the policies listed are provided by the property
Front desk staff will greet guests on arrival at the property.
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.

We should mention

  • Children aged 18 years old and younger stay free in the same room as the parent or guardian when using existing bedding.
  • Registered guests are the only ones allowed to be in guestrooms.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Buffalo Downtown Hotel
Comfort Suites Hotel Downtown
Comfort Suites Downtown Hotel Buffalo
Comfort Suites Downtown Buffalo
Comfort Suites Downtown Buffalo Hotel
Comfort Suites Buffalo
Buffalo Comfort Suites
Holiday Inn Express Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown
Holiday Inn Express Suites Buffalo Downtown Medical CTR
Holiday Inn Express Suites Buffalo Downtown Medical CTR by IHG

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG Reviews

Reviews

8.6

Excellent

Rating 10 - Excellent. 563 out of 1007 reviews
Rating 8 - Good. 271 out of 1007 reviews
Rating 6 - Okay. 76 out of 1007 reviews
Rating 4 - Poor. 44 out of 1007 reviews
Rating 2 - Terrible. 53 out of 1007 reviews

8.8/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.6/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Scott

Great room and stay for the money.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great Stay All Around!!! Great Friendly Staff, Close To Everything AAAAA+++++
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Ellen

Liked: Cleanliness, staff & service, amenities
Very clean and friendly staff
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Julie

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful room clean most comfortable bed I have ever slept in!
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, amenities, property conditions & facilities
Great service and great location
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Sharon

Liked: Cleanliness, amenities, property conditions & facilities
Rooms were very clean. Staff was very accommodating. Just very enjoyable stay.
Stayed 4 nights in Feb 2026
Verified

10/10 Excellent

Dharani

Liked: Cleanliness, amenities, property conditions & facilities
Clean room and staff are helpful
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Melissa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was just as pictured a one bedroom suite, clean, quiet hotel, parking garage was 2 short blocks down from the property reasonable pricing well lit, for being in the city felt very safe, not a lot of dining options close by, breakfast had a large variety. I would definitely stay again.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Stardeja

Liked: Cleanliness, amenities, property conditions & facilities
Great place! I will be back
Stayed 3 nights in Feb 2026
Verified

10/10 Excellent

Theron

Big, spacious room and suite. Excellent location
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Nick

Liked: Cleanliness, amenities, property conditions & facilities
Staff were helpful during a fire alarm and kept people relaxed.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Eden

Liked: Cleanliness, amenities, property conditions & facilities
Very clean and friendly
Stayed 1 night in Feb 2026
Verified

8/10 Good

Steve

Liked: Cleanliness, property conditions & facilities
Room was clean and lots of room, spacious.
Stayed 1 night in Feb 2026
Verified

8/10 Good

Scott

Liked: Cleanliness, amenities
Super friendly and curtious. Breakfast was awesome!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Joseph

Liked: Cleanliness, staff & service, amenities
Good Stay All Around
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Tim

Always a great experience, decades of staying here
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

RYAN

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Rooms were large. Breakfast was good and very friendly and helpful staff
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Mallory

Liked: Cleanliness, property conditions & facilities
The room was great and spacious
Stayed 1 night in Jan 2026
Verified

8/10 Good

Matt

Liked: Cleanliness, property conditions & facilities
Disliked: Amenities
The beds were extremely comfortable! Really the only bad thing is they advertised free parking on the weekend which is actually just street parking that isn’t allowed over night and the parking garage they send you to is two blocks away.
Stayed 3 nights in Feb 2026
Verified

10/10 Excellent

Adontaye

Liked: Cleanliness, amenities, property conditions & facilities
Everything was great!
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Daniel

Liked: Cleanliness, staff & service, property conditions & facilities
Clean, nice staff, good breakfast
Stayed 3 nights in Oct 2025
Verified

10/10 Excellent

Chase

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
yes there was alot nearby
Stayed 3 nights in Mar 2026
Verified

10/10 Excellent

Tricia

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was pleasant, our suite was clean and well kept. Great breakfast!
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Joseph

Around greatWm
Stayed 2 nights in Feb 2026
Verified

8/10 Good

Daniel

Liked: Cleanliness, staff & service, amenities
Rooms were clean and the breakfast was very good. Traveled with our kids and 4 grandkids. They had a great time
Stayed 1 night in Dec 2025