
Cheap flights from Santo Domingo de los Tsáchilas
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Cheap round-trip flights from Santo Domingo de los Tsáchilas
The lowest prices found within the past 7 days from Santo Domingo de los Tsáchilas to were €208 for one-way flights and €452 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.
UIO
Mariscal Sucre Intl.
PTY
Tocumen Intl.
€452 Return, found 6 days ago
€452
Return
found 6 days ago
UIO
Mariscal Sucre Intl.
PTY
Tocumen Intl.
€757 Return, found 6 days ago
€757
Return
found 6 days ago
UIO
Mariscal Sucre Intl.
PTY
Tocumen Intl.
€790 Return, found 6 days ago
€790
Return
found 6 days ago
UIO
Mariscal Sucre Intl.
PTY
Tocumen Intl.
€815 Return, found 6 days ago
€815
Return
found 6 days ago
UIO
Mariscal Sucre Intl.
PTY
Tocumen Intl.
€865 Return, found 6 days ago
€865
Return
found 6 days ago
UIO
Mariscal Sucre Intl.
PTY
Tocumen Intl.
€901 Return, found 6 days ago
€901
Return
found 6 days ago
Origin airport IATA code | UIO |
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Featured Hotels near Santo Domingo de los Tsáchilas

Hotel Plaza Grande
Garcia Moreno N5-16 Y Chile Quito Pichincha
The price is €172 per night from 15 Apr to 16 Apr
€172
15 Apr - 16 Apr
Our customers tell us that they can't get enough of the helpful staff at Hotel Plaza Grande. During your stay, you're just a quick walk from Carondelet Palace. Enjoy features like free breakfast and free WiFi in public areas, plus a restaurant.
9.8/10 Exceptional! (230 reviews)
Excellent service. Front desk and restaurant were very professional. Great stay.
Reviewed on 5 Apr 2026

Friends Hotel & Rooftop - Historic Center & Museums
Calle Junin OE1 - 61 y Quito
The price is €79 per night from 13 Apr to 14 Apr
€79
13 Apr - 14 Apr
Our customers tell us that they can't get enough of the helpful staff at Friends Hotel & Rooftop - Historic Center & Museums. During your stay, you're just a quick walk from Manuela Saenz Museum. You'll find features such as free breakfast and free WiFi in public areas, plus a restaurant.
9.4/10 Exceptional! (130 reviews)
Very close to old town shops and restaurants
Reviewed on 6 Apr 2026

Hotel Reina Isabel
Av. Amazonas N23-44 y Veintimilla Quito Pichincha
The price is €77 per night from 9 May to 10 May
€77
9 May - 10 May
Our customers tell us that they can't get enough of the helpful staff at Hotel Reina Isabel. During your stay, you're just a quick walk from Cuyabeno Lodge. You'll find features such as free WiFi in public areas and a free manager's reception, plus a restaurant. This property offers pet-friendly amenities, such as an off-lead area.
9/10 Wonderful! (1,002 reviews)
Rooms are perfect. The staff are awesome. Breakfast was amazing. Hot tub was really nice so refreshing.
Reviewed on 3 Apr 2026
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Hotel San Francisco de Quito
Sucre Oe 3-17 y Guayaquil Quito
The price is €65 per night from 11 Apr to 12 Apr
€65
11 Apr - 12 Apr
Our customers tell us they can't get enough of Hotel San Francisco de Quito's great location. During your stay, you're just a quick walk from Maria Augusta Urrutia Museum. You'll find features such as free breakfast and free WiFi in public areas, plus a restaurant.
8.8/10 Excellent! (455 reviews)
Most magical place I’ve ever stayed in.
Reviewed on 9 Apr 2026

Hilton Colon Quito
Amazonas N 1914 Y Patria Avenida 1 Quito
The price is €82 per night from 19 Apr to 20 Apr
€82
19 Apr - 20 Apr
Our customers tell us that they can't get enough of the helpful staff at Hilton Colon Quito. During your stay, you'll be connected to the convention centre and just a quick walk from El Ejido Park. Features include free WiFi in public areas and free self-parking, plus 2 restaurants.
8.6/10 Excellent! (463 reviews)
5 Stars
Reviewed on 2 Apr 2026

Saloya Mindo Life Landscape hotel
W598 V4 Pirca Mindo Pichincha
The price is €504 per night from 11 Apr to 12 Apr
€504
11 Apr - 12 Apr
During your stay at Saloya Mindo Life Landscape hotel, you'll be close to Mindo Valley. Free breakfast, free WiFi in public areas and free self-parking are available.
8/10 Very Good! (2 reviews)
this is for the adventerous, dont get scare on the way there the roads are a little rough due to the hotel still being developed. Chef Marcelo is a plus for this hotel and Sol as well. The entire staff is extremely friendly and helpful.
Reviewed on 27 Aug 2025
Don't see what you're looking for?
See all available properties in Santo Domingo de los Tsáchilas
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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