Find Cheap Flights from Mexico City (MEX) to Panama City (PTY) from €302

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Selected flight deals from Mexico City to Panama City

The lowest prices found within the past 7 days from Mexico City to Panama City were €112 for one-way flights and €302 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, 31 Dec - Tue, 13 Jan
MEX
Mexico City Intl.
PTY
Tocumen Intl.
€302 Return, found 6 days ago
€302
Return
found 6 days ago
Select Aeromexico flight, departing Wed, 31 Dec from Mexico City Intl. to Tocumen Intl., returning Tue, 13 Jan, priced at €302 found 6 days ago
Wed, 31 Dec - Tue, 13 Jan
MEX
Mexico City Intl.
PTY
Tocumen Intl.
€354 Return, found 6 days ago
€354
Return
found 6 days ago
Select Aeromexico flight, departing Wed, 31 Dec from Mexico City Intl. to Tocumen Intl., returning Tue, 13 Jan, priced at €354 found 6 days ago
Wed, 31 Dec - Tue, 13 Jan
MEX
Mexico City Intl.
PTY
Tocumen Intl.
€405 Return, found 6 days ago
€405
Return
found 6 days ago
Select Copa flight, departing Wed, 31 Dec from Mexico City Intl. to Tocumen Intl., returning Tue, 13 Jan, priced at €405 found 6 days ago
Wed, 31 Dec - Tue, 13 Jan
MEX
Mexico City Intl.
PTY
Tocumen Intl.
€435 Return, found 6 days ago
€435
Return
found 6 days ago
Select Aeromexico flight, departing Wed, 31 Dec from Mexico City Intl. to Tocumen Intl., returning Tue, 13 Jan, priced at €435 found 6 days ago
Wed, 31 Dec - Tue, 13 Jan
MEX
Mexico City Intl.
PTY
Tocumen Intl.
€446 Return, found 6 days ago
€446
Return
found 6 days ago
Select Copa flight, departing Wed, 31 Dec from Mexico City Intl. to Tocumen Intl., returning Tue, 13 Jan, priced at €446 found 6 days ago
Cheap Flights from Mexico City to Panama City & Flight Information
Origin airport IATA code
MEX
Destination airport IATA code
PTY
Number of flight options
1
Return price
€302
Average flight time
4 hours 45 mins

Panama City Flight Information

Traveling From
Mexico City
Origin Airport IATA Code
MEX
Traveling To
Panama City
Destination Airport IATA Code
PTY
Number of Airlines Serving
Available Airlines
Aeromexico, Copa, avianca
Distance
Direct Flight Time
Flight Price
€302

Need a car after flight from Mexico City to Panama City

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

Place to stay after flight from Mexico City to Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Yövy tässä 5 tähden ylellisessä hotellissa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja 3 ravintolasta. Asiakkaamme kehuvat ...
9/10 Wonderful! (4,509 reviews)
Rooms were really clean

Reviewed on 15 Nov 2025

Opens in a new windowHotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Yövy tässä 5 tähden ylellisessä hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, täyden palvelun kylpylästä ja 2 ravintolasta. Asiakkaamme kehuvat ...
8.8/10 Excellent! (1,001 reviews)
Great stay. Staff was excellent. Location is great too

Reviewed on 13 Nov 2025

Opens in a new windowWaldorf Astoria Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Yövy tässä 4,5 tähden ylellisessä hotellissa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja ilmaisesta pysäköinnistä. Asiakkaamme ...
8.4/10 Very Good! (1,200 reviews)
The room was spotless and the staff was courteous

Reviewed on 14 Nov 2025

Opens in a new windowMegapolis Hotel Panamá
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Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina, Panama City, Panama
Yövy tässä 3 tähden liikematkustukseen soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja huonepalvelusta. ...
8.8/10 Excellent! (1,551 reviews)
lugar muy agradable, tiene tienda de conveniencia al lado, el. metro está cerca para ir al aeropuerto, el personal fue muy amable, el check in fue flexible.

Reviewed on 11 Nov 2025

Opens in a new windowPrincipe Hotel and Suites
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Yövy tässä 4 tähden kylpylälomalle soveltuvassa lomakeskuksessa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja täyden palvelun ...
8.4/10 Very Good! (977 reviews)
Excelente atención y servicio La cuna de bebé era de material como fierro, insegura para bebés que ya se paran un poco El área de juegos de niños siempre mojada y no tenía protección solar podría adecuarse mejor

Reviewed on 1 Nov 2025

Opens in a new windowSheraton Grand Panama
W Panama

W Panama

5 out of 5
Calle Aquilino de la Guardia & Calle 50 Panama City
Yövy tässä 5 tähden ylellisessä hotellissa kohteessa Panamá. Nauti 2 ravintolasta, 3 porealtaasta ja 2 baarista/loungesta. Asiakkaamme kehuvat majoituspaikan ...
8.8/10 Excellent! (1,000 reviews)
Clean room, great views, great staff!

Reviewed on 10 Nov 2025

Opens in a new windowW Panama
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Flight prices above are per person all prepaid taxes and online service fees included and subject to availability