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Cheap Flights from Santiago to Guayaquil & Flight Information
Origin airport IATA code
SCL
Destination airport IATA code
GYE
Number of flight options
1
Average flight time
5 hours 18 mins

Guayaquil Flight Information

Traveling From
Santiago
Origin Airport IATA Code
SCL
Traveling To
Guayaquil
Destination Airport IATA Code
GYE
Number of Airlines Serving
Available Airlines
Distance
Direct Flight Time
Flight Price

Need a car after flight from Santiago to Guayaquil

Place to stay after flight from Santiago to Guayaquil

Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno Guayaquil Guayas
Yövy tässä kylpylälomalle soveltuvassa hotellissa kohteessa Guayaquil. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja täyden palvelun kylpylästä. ...
9.4/10 Exceptional! (1,006 reviews)
Todos son muy amable!

Reviewed on 12 Feb 2026

Opens in a new windowOro Verde Guayaquil
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto Guayaquil Guayas
Yövy tässä liikematkustukseen soveltuvassa hotellissa kohteessa Guayaquil. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja aamiaisesta (lisämaksusta). ...
9.2/10 Wonderful! (1,003 reviews)
We arrived at 3am to our transfer waiting for us, the staff were all friendly and attentive. The room was spacious and clean, and the bed was very comfortable.

Reviewed on 9 Feb 2026

Opens in a new windowHoliday Inn Guayaquil Airport by IHG
Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N Guayaquil Guayas
Yövy tässä ylellisessä hotellissa kohteessa Guayaquil. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja täyden palvelun kylpylästä. Asiakkaamme ...
9.2/10 Wonderful! (1,001 reviews)
Staff was very friendly, food spectacular, and the infrastructure was amazing! Spa was a plus...

Reviewed on 5 Feb 2026

Opens in a new windowWyndham Guayaquil Puerto Santa Ana
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Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111 Guayaquil
Yövy tässä ylellisessä hotellissa kohteessa Guayaquil. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja täyden palvelun kylpylästä. Asiakkaamme ...
8.6/10 Excellent! (855 reviews)
Did meet my expectation

Reviewed on 7 Feb 2026

Opens in a new windowHilton Colon Guayaquil
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 out of 5
Juan Tanca Marengo Ave Guayaquil Guayas
Yövy tässä liikematkustukseen soveltuvassa hotellissa kohteessa Guayaquil. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja 2 ravintolasta. Asiakkaamme ...
9/10 Wonderful! (1,000 reviews)
Cold AC. Great customer service. You will find anything that you need within walking distance. Super clean room

Reviewed on 7 Feb 2026

Opens in a new windowWyndham Garden Guayaquil
TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

4.5 out of 5
Av. Joaquín Orrantia y L. Benitez Guayaquil Guayas
Yövy tässä ylellisessä hotellissa kohteessa Guayaquil. Nauti ilmaisesta Wi-Fi-yhteydestä, 2 ravintolasta ja 2 baarista/loungesta. Asiakkaamme kehuvat majoituspaikan ...
8.8/10 Excellent! (1,002 reviews)
Nice and neat room, courteous staff.

Reviewed on 4 Feb 2026

Opens in a new windowTRYP by Wyndham Guayaquil Airport
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Flight prices above are per person all prepaid taxes and online service fees included and subject to availability