Cheap flights from Panama City

Many airlines offer flexible change policies

Earn BONUS+ rewards on top of your airline points

Enjoy exclusive promotions on the ebookers app!

Panama City Flight Information
Origin airport IATA code
PNS

Your cheap flight from Panama City is available right now.

Visit us now at Ebookers to choose from lots of cheap flights leaving Panama City or our last minute air tickets from Panama City at unbeatable prices, specially chosen for those who want the best deal possible. Ebookers continuously compares and updates the choice of air tickets available from Panama City, offered by more than 400 airlines worldwide. Ebookers works 24/7 to find the best deals so that our clients don’t have to waste their valuable time. Wherever you are going, you will find your perfect combination for a fantastic holiday at a budget price right here with our extensive flights database and helpful information; star ratings, reviews, maps and more… Many discount flights with a departure from Panama City and last minute flights from Panama City are available at Ebookers to help you organise your flights the way you want them at a price you can afford. Come and prepare your perfect holiday now at Ebookers.

Fancy a break from Panama City? Book your flight in advance from Panama City!

Thinking about getting away for a while and leaving from Panama City? Visit Ebookers and discover our selection of inexpensive Panama City flights and air tickets from Panama City at unbelievable prices with a great choice of airlines - over 400 in fact. We give excellent service at an affordable price. For a great weekend away from Panama City, visit to Ebookers where we have many available flights departing Panama City on special offer. Check out our deals and find a flight leaving Panama City at a price you never imagined. These special Ebookers offers aren’t just about cheap flights. We have over 95,000 hotels worldwide in our database, so why not stay in a Panama City hotel and start or end your break in style? Combine your choice of flight, hotel and car rental from our vast, reliable database to create your perfect holiday or dream weekend at a discounted price with Ebookers. Don’t wait or you may be too late!

Featured Hotels near Panama City

Hilton Garden Inn Panama City Airport

Hilton Garden Inn Panama City Airport

3 out of 5
5625 Venture Crossings Blvd Panama City FL
The price is €96 per night from 24 Nov to 25 Nov
€96
24 Nov - 25 Nov
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Hilton Garden Inn Panama City Airport. Features include free WiFi in public areas and free self-parking, plus a restaurant.
9.4/10 Exceptional! (665 reviews)
Food is great people are very friendly and helpful

Reviewed on 10 Nov 2025

Opens in a new windowHilton Garden Inn Panama City Airport
La Quinta Inn & Suites by Wyndham Panama City

La Quinta Inn & Suites by Wyndham Panama City

3 out of 5
1030 E 23rd St Panama City FL
The price is €71 per night from 19 Nov to 20 Nov
€71
19 Nov - 20 Nov
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at La Quinta Inn & Suites by Wyndham Panama City. During your stay, you're just a quick walk from Panama City Mall. You'll find features such as free WiFi in public areas and free self-parking, plus a gym. This property offers pet-friendly amenities, such as an off-lead area.
8.6/10 Excellent! (1,002 reviews)
Clean room and friendly staff. Breakfast could be improved.

Reviewed on 12 Nov 2025

Opens in a new windowLa Quinta Inn & Suites by Wyndham Panama City
Holiday Inn Panama City by IHG

Holiday Inn Panama City by IHG

3 out of 5
2001 Martin Luther King Boulevard Panama City FL
The price is €91 per night from 12 Dec to 13 Dec
€91
12 Dec - 13 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Holiday Inn Panama City by IHG. During your stay, you're just a quick walk from Panama City Mall. Free WiFi in public areas, free self-parking and an indoor pool are available.
8.4/10 Very Good! (741 reviews)
It was amazing

Reviewed on 3 Nov 2025

Opens in a new windowHoliday Inn Panama City by IHG
Save an average of 15% on thousands of hotels when you're signed in
Best Western Plus Panama City Hotel

Best Western Plus Panama City Hotel

2.5 out of 5
Mercedes Avenue, 2338 Panama City FL
The price is €72 per night from 20 Nov to 21 Nov
€72
20 Nov - 21 Nov
includes taxes & fees
Our customers tell us that they can't get enough of the free breakfast at Best Western Plus Panama City Hotel. During your stay, you're just a quick walk from Panama City Mall. Features include free WiFi in public areas and free self-parking, plus an outdoor pool.
8.2/10 Very Good! (871 reviews)
The staff was amazing!!!! Super sweet and helpful!!! The room was spotless, comfortable and breakfast was great! Will definitely be coming back to stay

Reviewed on 11 Nov 2025

Opens in a new windowBest Western Plus Panama City Hotel
Comfort Inn & Suites Panama City North

Comfort Inn & Suites Panama City North

2.5 out of 5
2317 Jenks Ave Panama City FL
The price is €59 per night from 30 Nov to 1 Dec
€59
30 Nov - 1 Dec
includes taxes & fees
During your stay at Comfort Inn & Suites Panama City North, you'll be within walking distance of Panama City Mall. Free breakfast, free WiFi in public areas and free self-parking are available.
8/10 Very Good! (666 reviews)
All of the above was great

Reviewed on 10 Nov 2025

Opens in a new windowComfort Inn & Suites Panama City North
Quality Inn Panama City North

Quality Inn Panama City North

2.5 out of 5
1013 E 23rd St Panama City FL
The price is €56 per night from 7 Dec to 8 Dec
€56
7 Dec - 8 Dec
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Quality Inn Panama City North. During your stay, you'll be connected to the convention centre and just a quick walk from Panama City Mall. Features include free breakfast, free WiFi in public areas and free self-parking.
7.6/10 Good! (682 reviews)
Breakfast

Reviewed on 10 Nov 2025

Opens in a new windowQuality Inn Panama City North
Don't see what you're looking for?
See all available properties in Panama City
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.