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Selected flight deals from Santiago to Panama City

The lowest prices found within the past 7 days from Santiago to Panama City were €269 for one-way flights and €560 for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, 27 Jun - Tue, 21 Jul

SCL

Arturo Merino Benitez

PTY

Tocumen Intl.

€560

Return

found 6 days ago

Sat, 27 Jun - Tue, 21 Jul

SCL

Arturo Merino Benitez

PTY

Tocumen Intl.

€628

Return

found 6 days ago

Sat, 27 Jun - Tue, 21 Jul

SCL

Arturo Merino Benitez

PTY

Tocumen Intl.

€648

Return

found 6 days ago

Sat, 27 Jun - Tue, 21 Jul

SCL

Arturo Merino Benitez

PTY

Tocumen Intl.

€755

Return

found 6 days ago

Sat, 27 Jun - Tue, 21 Jul

SCL

Arturo Merino Benitez

PTY

Tocumen Intl.

€836

Return

found 6 days ago

Cheap Flights from Santiago to Panama City & Flight Information
Origin airport IATA code	SCL
Destination airport IATA code	PTY
Number of flight options	1
Return price	€560
Average flight time	5 hours 54 mins

Panama City Flight Information

Traveling From	Santiago
Origin Airport IATA Code	SCL
Traveling To	Panama City
Destination Airport IATA Code	PTY
Number of Airlines Serving
Available Airlines	avianca, Copa, Delta, American Airlines
Distance
Direct Flight Time
Flight Price	€560

Need a car after flight from Santiago to Panama City

Economy

Chevrolet Spark

4 people

Compact

Ford Focus

4 people

Midsize

Toyota Corolla

5 people

SUV

Jeep Compass

5 people

Place to stay after flight from Santiago to Panama City

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

Yövy tässä ylellisessä hotellissa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja 3 ravintolasta. Asiakkaamme kehuvat majoituspaikan ...

9/10 Wonderful! (5,444 reviews)

Best breakfast honestly

Reviewed on 17 May 2026

The Executive Hotel

Calle 52 Panama City Panama

Yövy tässä liikematkustukseen soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja ilmaisesta pysäköinnistä. ...

9.2/10 Wonderful! (1,109 reviews)

The room was rather small and Hotel is centrally located. I will say that the highlight was the friendly staff. Just so you know come out of the rooms and bathrooms are pretty tiny, the balconies are pretty small as well so it’s a good spot if you’re looking to not stay super long or you are traveling ...

Reviewed on 16 May 2026

Principe Hotel and Suites

Via Argentina Panama City Panama

Yövy tässä liikematkustukseen soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja huonepalvelusta. Asiakkaamme ...

9/10 Wonderful! (1,857 reviews)

I couldn't get a response regarding an airport shuttle so contacted hotels.com who also failed. It was going to cost $30. My Uber cost less than $20. Clean room, but very uninviting and worn. AC was not on when I entered. It finally got too cold, but there was no way to adjust it. No coffee or water. ...

Reviewed on 16 May 2026

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Waymore Hotel Spa & Casino

Calle Augusto Samuel Boyd y Calle Eusebi Panama City

Yövy tässä kylpylälomalle soveltuvassa aamiaismajoituksessa kohteessa Panamá. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja ilmaisesta pysäköinnistä. ...

8.8/10 Excellent! (921 reviews)

Todo fue excelente, estuvimos 8 días y todos los días hicieron limpieza, las instalaciones hermosas, el personal muy atentos y el desayuno muy bueno y saludable. Lo recomiendo al 💯. Muchas gracias.

Reviewed on 17 May 2026

Hotel Ojos del Rio

calle 41 este Panama City Panama

Yövy tässä hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, aamiaisesta (lisämaksusta) ja huonepalvelusta. Asiakkaamme kehuvat majoituspaikan ...

8/10 Very Good! (1,008 reviews)

The hotel was not bad, just for a stop and go purpose or if you just need a place to rest. The Bad: The towels were too thin for drying after a bath, and hot water takes too long to get. The shower head definitely needs changing (seems it has been there years). The television needs updating so you ...

Reviewed on 17 May 2026

Courtyard by Marriott Panama Multiplaza Mall

Via Israel Multiplaza Pacific Mall Panama City Panama

Yövy tässä liikematkustukseen soveltuvassa hotellissa kohteessa Panamá. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja aamiaisesta (lisämaksusta). ...

9/10 Wonderful! (1,006 reviews)

Todo

Reviewed on 15 May 2026

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.