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Selected flight deals from Mexico City to Santiago

The lowest prices found within the past 7 days from Mexico City to Santiago were €412 for one-way flights and for return flights, for the period specified. Prices and availability are subject to change. Additional terms apply.

Cheap Flights from Mexico City to Santiago & Flight Information
Origin airport IATA code
MEX
Destination airport IATA code
SCL
Number of flight options
1
Average flight time
11 hours 25 mins

Santiago Flight Information

Traveling From
Mexico City
Origin Airport IATA Code
MEX
Traveling To
Santiago
Destination Airport IATA Code
SCL
Number of Airlines Serving
Available Airlines
Copa, avianca, LATAM Airlines Group
Distance
Direct Flight Time
Flight Price

Need a car after flight from Mexico City to Santiago

Place to stay after flight from Mexico City to Santiago

Holiday Inn Santiago - Airport Terminal by IHG

Holiday Inn Santiago - Airport Terminal by IHG

4 out of 5
Armando Cortinez Norte 2150 Santiago Region Metropolitana
Yövy tässä hiihtoon sopivassa hotellissa kohteessa Santiago de Chile. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja aamiaisesta (lisämaksusta). ...
9/10 Wonderful! (1,443 reviews)
It’s all about the location! We arrived late into Santiago and had a connecting flight early in the morning. Loved the fact that we could just walk out of the terminal, cross the street and arrive at the hotel. The hotel itself is very tired. The furniture and carpets desperately need to be cleaned ...

Reviewed on 17 Feb 2026

Opens in a new windowHoliday Inn Santiago - Airport Terminal by IHG
Hotel Capital Bellet

Hotel Capital Bellet

3 out of 5
Saint Paul 1457 / Antonio Bellet 135 Santiago Providencia
Yövy tässä liikematkustukseen soveltuvassa hotellissa kohteessa Santiago de Chile. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja aamiaisesta ...
9/10 Wonderful! (966 reviews)
Excellent staff on front desk. Leant me a phone charger. Clean room. Strong powerful shower. Would stay again. Good price. In the middle of two metro stops. Each one about a 7 min walk away.

Reviewed on 11 Feb 2026

Opens in a new windowHotel Capital Bellet
DoubleTree by Hilton Hotel Santiago - Vitacura

DoubleTree by Hilton Hotel Santiago - Vitacura

4 out of 5
Avenida Vitacura 2727, Las Condes Santiago
Yövy tässä hotellissa kohteessa Santiago de Chile. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja aamiaisesta (lisämaksusta). Asiakkaamme kehuvat ...
9.4/10 Exceptional! (1,001 reviews)
Centrally located, attentive staff, clean rooms and a warm welcome cookie and drinks!

Reviewed on 13 Feb 2026

Opens in a new windowDoubleTree by Hilton Hotel Santiago - Vitacura
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ICON Hotel

ICON Hotel

4 out of 5
Av. Alonso de Cordova 6050 Santiago
Yövy tässä kylpylälomalle soveltuvassa hotellissa kohteessa Santiago de Chile. Nauti ilmaisesta Wi-Fi-yhteydestä, täyden palvelun kylpylästä ja kattoterassista. ...
8.6/10 Excellent! (1,005 reviews)
Good location. Great service; except in the Roof Top Bar

Reviewed on 17 Feb 2026

Opens in a new windowICON Hotel
Wyndham Santiago Aeropuerto

Wyndham Santiago Aeropuerto

4.5 out of 5
Av. Americo Vespucio 1284 Santiago Santiago
Yövy tässä ylellisessä hotellissa kohteessa Santiago de Chile. Nauti ilmaisesta Wi-Fi-yhteydestä, ilmaisesta pysäköinnistä ja täyden palvelun kylpylästä. Asiakkaamme ...
9/10 Wonderful! (1,229 reviews)
Perfect

Reviewed on 17 Feb 2026

Opens in a new windowWyndham Santiago Aeropuerto
Almacruz Hotel y Centro de Convenciones

Almacruz Hotel y Centro de Convenciones

4 out of 5
San Antonio 65 Santiago Region Metropolitana
Yövy tässä liikematkustukseen soveltuvassa hotellissa kohteessa Santiago de Chile. Nauti ilmaisesta aamiaisesta, ilmaisesta Wi-Fi-yhteydestä ja ilmaisesta pysäköinnistä. ...
8.2/10 Very Good! (662 reviews)
Room was great but we were unable to adjust air conditioning. Restaurant was great, as was breakfast. No bottles of water available tho … Hotel not in a lovely area

Reviewed on 8 Feb 2026

Opens in a new windowAlmacruz Hotel y Centro de Convenciones
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Terms & Conditions

Flight prices above are per person all prepaid taxes and online service fees included and subject to availability