Compare cheap hotels in Serra Mesa
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Featured Hotels near Serra Mesa

Sheraton San Diego Resort
1380 Harbor Island Dr San Diego CA
10.05 km from Serra Mesa
The price is €153 per night
€153
1 Jan - 2 Jan 2026
includes taxes & fees
Our customers tell us they can't get enough of Sheraton San Diego Resort's great location. During your stay, you're just a quick walk from San Diego Bay. Free WiFi in public areas, a free round-trip airport shuttle and 3 outdoor pools are available. This property offers pet-friendly amenities, such as food and water bowls.
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Bay Club Hotel & Marina
2131 Shelter Island Dr San Diego CA
12.59 km from Serra Mesa
The price is €105 per night
€105
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us they can't get enough of Bay Club Hotel & Marina's great location. During your stay, you're just a quick walk from Shelter Island. You'll find features such as free WiFi in public areas, plus an outdoor pool and a restaurant.
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The DEXTRO Little Italy, BW Premier Collection
1617 1st Avenue San Diego CA
9.25 km from Serra Mesa
The price is €109 per night
€109
4 Jan - 5 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at The DEXTRO Little Italy, BW Premier Collection. During your stay, you're just a quick walk from San Diego Civic Theatre. Features include free WiFi in public areas, plus an outdoor pool and a restaurant.
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Courtyard by Marriott San Diego Downtown Little Italy
1646 Front St San Diego CA
9.29 km from Serra Mesa
The price is €116 per night
€116
6 Jan - 7 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Courtyard by Marriott San Diego Downtown Little Italy. During your stay, you're just a quick walk from Waterfront Park. You'll find features such as free WiFi in public areas, plus an outdoor pool and a restaurant. This property offers pet-friendly amenities, such as an off-lead area.
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Legacy Resort Hotel & Spa
875 Hotel Circle South San Diego CA
5.68 km from Serra Mesa
Legacy Resort Hotel & Spa's great location gets high marks from our customers. During your stay, you'll be within walking distance of Hotel Circle. Enjoy features like free WiFi in public areas, plus a full-service spa and an outdoor pool.
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San Diego Marriott La Jolla
4240 La Jolla Village Dr La Jolla CA
10.64 km from Serra Mesa
The price is €157 per night
€157
9 Jan - 10 Jan 2026
includes taxes & fees
San Diego Marriott La Jolla's great location gets high marks from our customers. During your stay, you're just a quick walk from University of California, San Diego. Enjoy features like free WiFi in public areas, plus an outdoor pool and a restaurant.
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DoubleTree by Hilton Hotel San Diego - Mission Valley
7450 Hazard Center Dr San Diego CA
4.15 km from Serra Mesa
The price is €110 per night
€110
3 Jan - 4 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at DoubleTree by Hilton Hotel San Diego - Mission Valley. During your stay, you'll be connected to a shopping centre and within walking distance of Fashion Valley Mall. Features include free WiFi in public areas, plus an indoor pool and a restaurant.
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Hilton San Diego Mission Valley
901 Camino Del Rio S San Diego CA
4.67 km from Serra Mesa
The price is €120 per night
€120
23 Jan - 24 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Hilton San Diego Mission Valley. During your stay, you'll be within walking distance of Mission Valley Mall. Features include free WiFi in public areas, plus an outdoor pool and a restaurant.
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The Dana on Mission Bay
1710 W Mission Bay Dr San Diego CA
10.12 km from Serra Mesa
The price is €153 per night
€153
4 Jan - 5 Jan 2026
includes taxes & fees
The Dana on Mission Bay's great beach location gets high marks from our customers. During your stay, you'll be within walking distance of Mission Bay. Enjoy features like 2 outdoor pools, 2 poolside bars and a restaurant. This property offers pet-friendly amenities, such as food and water bowls.
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Lafayette Hotel & Club
2223 El Cajon Blvd San Diego CA
5.34 km from Serra Mesa
The price is €224 per night
€224
5 Jan - 6 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Lafayette Hotel & Club. During your stay, you'll be close to San Diego Zoo. Enjoy features like free WiFi in public areas, plus 2 restaurants and 3 bars.
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Hard Rock Hotel San Diego
207 5th Ave San Diego CA
10.75 km from Serra Mesa
Our customers tell us they can't get enough of Hard Rock Hotel San Diego's great location. During your stay, you're just a quick walk from Petco Park. Enjoy features like free WiFi in public areas, plus 2 restaurants and 2 coffee shops/cafes.
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Pendry San Diego
550 J Street San Diego CA
10.57 km from Serra Mesa
The price is €316 per night
€316
20 Jan - 21 Jan 2026
includes taxes & fees
Our customers tell us they can't get enough of Pendry San Diego's great location. During your stay, you're just a quick walk from Petco Park. Features include free WiFi in public areas, plus 3 restaurants and 3 bars.
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Best Western Seven Seas
411 Hotel Circle South San Diego CA
5.33 km from Serra Mesa
The price is €76 per night
€76
1 Jan - 2 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the shopping around Best Western Seven Seas. During your stay, you'll be within walking distance of Hotel Circle. Free WiFi in public areas, free self-parking and an outdoor pool are available.
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Four Points by Sheraton San Diego
8110 Aero Dr San Diego CA
1.19 km from Serra Mesa
The price is €113 per night
€113
9 Jan - 10 Jan 2026
includes taxes & fees
Our customers tell us that they can't get enough of the helpful staff at Four Points by Sheraton San Diego. During your stay, you're just a quick walk from Convoy District. Enjoy features like free WiFi in public areas, plus an outdoor pool and a restaurant.
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Best Western Plus Marina Gateway Hotel
800 Bay Marina Dr National City CA
16.15 km from Serra Mesa
The price is €100 per night
€100
6 Jan - 7 Jan 2026
includes taxes & fees
Best Western Plus Marina Gateway Hotel's great location gets high marks from our customers. During your stay, you'll be within walking distance of San Diego Bay. You'll find features such as free WiFi in public areas and free self-parking, plus an outdoor pool.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Serra Mesa hotels essential information
Accommodation | 9,061 hotels |
|---|---|
Lowest Price | €76 |
Highest Price | €316 |
Popular hotels | Sheraton San Diego Resort, Bay Club Hotel & Marina, The DEXTRO Little Italy, BW Premier Collection, Courtyard by Marriott San Diego Downtown Little Italy, Legacy Resort Hotel & Spa, San Diego Marriott La Jolla, DoubleTree by Hilton Hotel San Diego - Mission Valley, Hilton San Diego Mission Valley, The Dana on Mission Bay, Lafayette Hotel & Club, Hard Rock Hotel San Diego, Pendry San Diego, Best Western Seven Seas, Four Points by Sheraton San Diego, Best Western Plus Marina Gateway Hotel |
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